Hiraku Motomura
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Explore the profile of Hiraku Motomura including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
236
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0
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Recent Articles
1.
Makino H, Seki S, Kitajima I, Motomura H, Nogami M, Yahara Y, et al.
BMC Musculoskelet Disord
. 2019 May;
20(1):247.
PMID: 31122237
Background: Although the pathogenesis of adolescent idiopathic scoliosis (AIS) remains unclear, there are little evidences of the pathogenesis in patients with thoracolumbar/lumbar AIS. The purpose of this study was to...
2.
Motomura H, Seki S, Shiozawa S, Aikawa Y, Nogami M, Kimura T
Biochem Biophys Res Commun
. 2018 Feb;
497(2):756-761.
PMID: 29476740
The objective of the present study is to demonstrate that a newly developed selective c-Fos/activator protein (AP)-1 inhibitor, T-5224, inhibits the expression of matrix metalloproteinases (MMPs) in human articular chondrocytes,...
3.
Makino H, Seki S, Yahara Y, Shiozawa S, Aikawa Y, Motomura H, et al.
Sci Rep
. 2017 Dec;
7(1):16983.
PMID: 29208967
Intervertebral disc (IVD) degeneration is a major cause of low back pain. The transcription factor c-Fos/Activator Protein-1 (AP-1) controls the expression of inflammatory cytokines and matrix metalloproteinases (MMPs) that contribute...
4.
Seki S, Hirano N, Matsushita I, Kawaguchi Y, Nakano M, Yasuda T, et al.
Spine J
. 2017 Jul;
18(1):99-106.
PMID: 28673829
Background Context: Although the cervical spine is only occasionally involved in rheumatoid arthritis (RA), involvement of the lumbar spine is even less common. A few reports on lumbar spinal stenosis...
5.
Matsushita I, Motomura H, Seki E, Kimura T
Mod Rheumatol
. 2016 Sep;
27(4):570-575.
PMID: 27589926
Objectives: The long-term effects of tumor necrosis factor (TNF)-blocking therapies on weight-bearing joints in patients with rheumatoid arthritis (RA) have not been fully characterized. The purpose of this study was...
6.
Nogami M, Kimura T, Seki S, Matsui Y, Yoshida T, Koike-Soko C, et al.
Tissue Eng Part A
. 2016 Mar;
22(7-8):680-8.
PMID: 27019057
Objective: Extracellular matrix (ECM) derived from human amniotic mesenchymal cells (HAMs) has various biological activities. In this study, we developed a novel HAM-derived ECM-coated polylactic-co-glycolic acid (ECM-PLGA) scaffold, examined its...
7.
Seki S, Tsumaki N, Motomura H, Nogami M, Kawaguchi Y, Hori T, et al.
Biochem Biophys Res Commun
. 2014 Mar;
446(4):876-81.
PMID: 24631904
Lumbar disc disease (LDD) is one of the most common musculoskeletal disorders, and accompanies intervertebral disc degeneration. CILP encodes cartilage intermediate layer protein, which is highly associated with LDD. Moreover,...
8.
Matsushita I, Morita Y, Ito Y, Motomura H, Kimura T
Mod Rheumatol
. 2013 Nov;
24(2):281-4.
PMID: 24252044
Objectives: The aim of this study was to clarify the long-term clinical and radiographic results of cementless total hip arthroplasty (THA) for patients with rheumatoid arthritis (RA). Methods: Twenty-eight total...
9.
Inhibitory effect of tacrolimus on progression of joint damage in patients with rheumatoid arthritis
Motomura H, Matsushita I, Seki E, Mine H, Kimura T
Int J Rheum Dis
. 2013 Nov;
17(7):749-54.
PMID: 24251619
Aim: To examine the inhibitory effect of tacrolimus on radiographic joint damage in patients with rheumatoid arthritis (RA). Methods: Thirty-eight patients with RA resistant or intolerant to conventional disease-modifying anti-rheumatic...
10.
Suzuki K, Matsui Y, Higashimoto M, Kawaguchi Y, Seki S, Motomura H, et al.
PLoS One
. 2012 May;
7(5):e36682.
PMID: 22570737
Background: Liposarcomas are the most common class of soft tissue sarcomas, and myxoid liposarcoma is the second most common liposarcoma. EWSR1-DDIT3 is a chimeric fusion protein generated by the myxoid...