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Hideto Yonekura

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Recent Articles
1.
Yonekura H, Kato I, Yamamoto Y, Ikeda T, Higashida H, Okamoto H
Endocrinology . 2023 Aug; 164(9). PMID: 37548257
In this review, we provide the status of research on vasoactive intestinal peptide (VIP) and oxytocin, typical C-terminal α-amidated peptide hormones, including their precursor protein structures, processing and C-terminal α-amidation,...
2.
Saito-Takatsuji H, Yoshitomi Y, Yamamoto R, Furuyama T, Ishigaki Y, Kato N, et al.
Int J Mol Sci . 2023 Feb; 24(4). PMID: 36835151
Chronic stress can affect gene expression in the hippocampus, which alters neural and cerebrovascular functions, thereby contributing to the development of mental disorders such as depression. Although several differentially expressed...
3.
Ikeda T, Yoshitake Y, Yoshitomi Y, Saito-Takatsuji H, Ishigaki Y, Yonekura H
Sci Rep . 2021 Oct; 11(1):19453. PMID: 34593918
Angiogenesis is physiologically essential for embryogenesis and development and reinitiated in adult animals during tissue growth and repair. Forming new vessels from the walls of existing vessels occurs as a...
4.
Saito-Takatsuji H, Yoshitomi Y, Ishigaki Y, Yamamoto S, Numata N, Sakai Y, et al.
Nutrients . 2021 Jul; 13(7). PMID: 34209567
Collagen tripeptide (CTP) is defined as a functional food material derived from collagenase digests of type I collagen and contains a high concentration of tripeptides with a Gly-X-Y sequence. CTP...
5.
Shibata S, Shibata N, Ohtsuka S, Yoshitomi Y, Kiyokawa E, Yonekura H, et al.
Cells . 2021 Apr; 10(4). PMID: 33918979
Decorin (DCN) is involved in a variety of physiological and pathological processes. Epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs) has been proposed as a major cause for the development...
6.
Yoshitomi Y, Ikeda T, Saito-Takatsuji H, Yonekura H
Int J Mol Sci . 2021 Apr; 22(6). PMID: 33802099
Blood vessels are essential for the formation and maintenance of almost all functional tissues. They play fundamental roles in the supply of oxygen and nutrition, as well as development and...
7.
Ikeda T, Saito-Takatsuji H, Yoshitomi Y, Yonekura H
Int J Mol Sci . 2020 Sep; 21(18). PMID: 32899690
Mature mRNA is generated by the 3' end cleavage and polyadenylation of its precursor pre-mRNA. Eukaryotic genes frequently have multiple polyadenylation sites, resulting in mRNA isoforms with different 3'-UTR lengths...
8.
Yoshitomi Y, Osada H, Satake H, Kojima M, Saito-Takatsuji H, Ikeda T, et al.
Biol Open . 2019 Feb; 8(2). PMID: 30718229
Ultraviolet (UV) radiation of eyes is a major risk factor for cataractogenesis, although the molecular mechanisms underlying this process remain poorly understood and genes that are affected by UV radiation...
9.
Yoshitomi Y, Ikeda T, Saito H, Yoshitake Y, Ishigaki Y, Hatta T, et al.
J Cell Sci . 2017 Jan; 130(5):916-926. PMID: 28096474
Blood vessels and nerve fibers are often closely arranged in parallel throughout the body. Therefore, neurovascular interactions have been suggested to be important for the development of vascular networks. However,...
10.
Tomosugi N, Yamamoto S, Takeuchi M, Yonekura H, Ishigaki Y, Numata N, et al.
J Atheroscler Thromb . 2016 Oct; 24(5):530-538. PMID: 27725401
Aim: Collagen tripeptide (CTP) is a functional food with a high content of Gly-X-Y tripeptides derived from collagen. The objective of this study was to evaluate the effect of CTP...