Hidehiko Saito
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Explore the profile of Hidehiko Saito including associated specialties, affiliations and a list of published articles.
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Articles
133
Citations
1843
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Recent Articles
1.
Saito H, Kojima T
Int J Hematol
. 2021 Mar;
113(6):785-788.
PMID: 33743110
Most clotting factors were initially discovered as agents functionally deficient in the plasmas of rare patients with hereditary coagulation disorders. During 1940s to 1960s, many factors were named by different...
2.
Kanematsu T, Suzuki N, Tamura S, Suzuki A, Ishikawa Y, Katsumi A, et al.
Nagoya J Med Sci
. 2021 Mar;
83(1):75-86.
PMID: 33727739
disorders are characterized by giant platelets, thrombocytopenia, and Döhle body-like cytoplasmic inclusion bodies in granulocytes. However, whether these disorders cause any changes in erythroid cells has yet to be determined....
3.
Ito T, Maruyama I, Shimazaki S, Yamamoto Y, Aikawa N, Hirayama A, et al.
Res Pract Thromb Haemost
. 2020 Nov;
4(7):1141-1149.
PMID: 33134780
Background: The efficacy and safety of thrombomodulin alfa (TM-α), a cofactor protein promoting thrombin-mediated protein C activation, have been examined in a phase 3 randomized, double-blinded, parallel-group trial in Japan....
4.
Vincent J, Francois B, Zabolotskikh I, Daga M, Lascarrou J, Kirov M, et al.
JAMA
. 2019 May;
321(20):1993-2002.
PMID: 31104069
Importance: Previous research suggested that soluble human recombinant thrombomodulin may reduce mortality among patients with sepsis-associated coagulopathy. Objective: To determine the effect of human recombinant thrombomodulin vs placebo on 28-day...
5.
Saito H, Hotta T, Naoe T
Int J Hematol
. 2018 Oct;
108(6):566-570.
PMID: 30315434
This year, 2018, marks the 60th anniversary of the Asiatic International Society of Hematology founded in 1958 and it seems to be a fitting occasion on which to reflect on...
6.
Saito H, Ito M, Kato S, Kodera Y, Okamoto S, Taniguchi S, et al.
Bone Marrow Transplant
. 2018 Jan;
53(5):609-616.
PMID: 29367710
The Japan Marrow Donor Program (JMDP), established in 1991, has continued to grow in its capacity to facilitate unrelated bone marrow (BMT) and peripheral blood stem cell transplantation (PBSCT) for...
7.
8.
Takagi Y, Murata M, Kozuka T, Nakata Y, Hasebe R, Tamura S, et al.
Thromb Haemost
. 2016 Sep;
116(6):1022-1031.
PMID: 27604259
Antithrombin (AT) and thrombomodulin (TM) play important roles in the process of natural anticoagulation in vivo. Recently, we reported that the prothrombin Yukuhashi mutation (p.Arg596Leu) was associated with AT and...
9.
Tamura K, Saito H, Asakura H, Okamoto K, Tagawa J, Hayakawa T, et al.
Int J Clin Oncol
. 2014 Nov;
20(4):821-8.
PMID: 25385713
Background: Disseminated intravascular coagulation (DIC) associated with solid tumors (DIC-ST) is often encountered in clinical practice. Patients with DIC-ST are usually in poor condition and have bleeding diathesis due to...
10.
Yamamoto K, Takeshita K, Saito H
Semin Thromb Hemost
. 2014 Aug;
40(6):652-9.
PMID: 25122500
Plasminogen activator inhibitor-1 (PAI-1), a principal inhibitor of fibrinolysis, is induced in thrombotic, fibrotic, and cardiovascular diseases, which in turn primarily afflict the older population. This induction of PAI-1 may...