Hideaki Tsuchiya
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Explore the profile of Hideaki Tsuchiya including associated specialties, affiliations and a list of published articles.
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56
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1571
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Recent Articles
1.
Ishigaki H, Ito S, Sasamura T, Ishida H, Nakayama M, Nguyen C, et al.
HLA
. 2024 Jan;
103(1):e15316.
PMID: 38226402
Macaques are useful animal models for studying the pathogenesis of rheumatoid arthritis (RA) and the development of anti-rheumatic drugs. The purpose of this study was to identify the major histocompatibility...
2.
Sato A, Tsukiyama T, Komeno M, Iwatani C, Tsuchiya H, Kawamoto I, et al.
Sci Rep
. 2023 Sep;
13(1):15649.
PMID: 37730951
Familial hypercholesterolemia (FH) is an inherited autosomal dominant disorder that is associated with a high plasma level of low-density lipoprotein (LDL) cholesterol, leading to an increased risk of cardiovascular diseases....
3.
Tsuji S, Mukai T, Tsuchiya H, Iwatani C, Nakamura A, Nagamura-Inoue T, et al.
Reprod Med Biol
. 2023 Sep;
22(1):e12540.
PMID: 37693240
Purpose: This study aimed to explore whether umbilical cord-derived mesenchymal stem cells (UC-MSCs) could be used as a therapeutic resource for endometriosis. Methods: Of seven cynomolgus monkeys with endometriosis, five...
4.
Gyobu-Motani S, Yabuta Y, Mizuta K, Katou Y, Okamoto I, Kawasaki M, et al.
EMBO J
. 2023 Mar;
42(9):e112962.
PMID: 36929479
Human in vitro oogenesis provides a framework for clarifying the mechanism of human oogenesis. To create its benchmark, it is vital to promote in vitro oogenesis using a model physiologically...
5.
Mizuta K, Katou Y, Nakakita B, Kishine A, Nosaka Y, Saito S, et al.
EMBO J
. 2022 Aug;
41(18):e110815.
PMID: 35912849
In vitro oogenesis is key to elucidating the mechanism of human female germ-cell development and its anomalies. Accordingly, pluripotent stem cells have been induced into primordial germ cell-like cells and...
6.
Cheng K, Seita Y, Moriwaki T, Noshiro K, Sakata Y, Hwang Y, et al.
Sci Adv
. 2022 Apr;
8(16):eabn8485.
PMID: 35442744
Development of the adrenal cortex, a vital endocrine organ, originates in the adrenogonadal primordium, a common progenitor for both the adrenocortical and gonadal lineages in rodents. In contrast, we find...
7.
Okamoto I, Nakamura T, Sasaki K, Yabuta Y, Iwatani C, Tsuchiya H, et al.
Science
. 2021 Nov;
374(6570):eabd8887.
PMID: 34793202
X chromosome dosage compensation ensures balanced gene dosage between the X chromosome and autosomes and between the sexes, involving divergent mechanisms among mammals. We elucidated a distinct mechanism for X...
8.
Kawabata T, Suga H, Takeuchi K, Nagata Y, Sakakibara M, Ushida K, et al.
Sci Rep
. 2021 May;
11(1):10729.
PMID: 34031474
For pituitary regenerative medicine, the creation of a hypophyseal model in monkeys is necessary to conduct future preclinical studies; however, previous studies reported that hypophysectomy in monkeys is not always...
9.
Sasaki K, Oguchi A, Cheng K, Murakawa Y, Okamoto I, Ohta H, et al.
Cell Rep
. 2021 May;
35(5):109075.
PMID: 33951437
In the early fetal stage, the gonads are bipotent and only later become the ovary or testis, depending on the genetic sex. Despite many studies examining how sex determination occurs...
10.
Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, et al.
Cell Stem Cell
. 2021 Apr;
28(6):1023-1039.e13.
PMID: 33831365
Trophoblasts are extraembryonic cells that are essential for maintaining pregnancy. Human trophoblasts arise from the morula as trophectoderm (TE), which, after implantation, differentiates into cytotrophoblasts (CTs), syncytiotrophoblasts (STs), and extravillous...