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Henry Sunpath

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Articles 44
Citations 714
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Recent Articles
11.
Siedner M, Moosa M, McCluskey S, Gilbert R, Pillay S, Aturinda I, et al.
Ann Intern Med . 2021 Oct; 174(12):1683-1692. PMID: 34698502
Background: Virologic failure in HIV predicts the development of drug resistance and mortality. Genotypic resistance testing (GRT), which is the standard of care after virologic failure in high-income settings, is...
12.
Airewele E, Sunpath H, Moosa M, Gandhi R
South Afr J HIV Med . 2021 Sep; 22(1):1281. PMID: 34522431
In many ways, the coronavirus disease 2019 (COVID-19) pandemic mirrors the challenges, lessons and opportunities of the HIV pandemic. In this article, we argue that global pandemics such as COVID-19...
13.
Li J, Stella N, Choudhary M, Javed A, Rodriguez K, Ribaudo H, et al.
J Antimicrob Chemother . 2021 Mar; 76(6):1558-1563. PMID: 33693678
Objectives: There is conflicting evidence on the impact of pre-existing HIV drug resistance mutations (DRMs) in patients infected with non-B subtype virus. Methods: We performed a case-cohort substudy of the...
14.
Chen Y, Coker D, Kramer M, Johnson B, Wall K, Ordonez C, et al.
AIDS Behav . 2019 May; 23(9):2558-2575. PMID: 31049812
Using a case-control study of patients receiving antiretroviral treatment (ART) in 2010-2012 at McCord Hospital in Durban, South Africa, we sought to understand how residential locations impact patients' risk of...
15.
John S, Kearns R, Johnson B, Ordonez C, Wu B, Hare A, et al.
New Voices Psychol . 2018 Jun; 12(2):2-20. PMID: 29937923
Analyzing factors associated with virological failure (VF) may improve antiretroviral therapy (ART) outcomes for individuals living with HIV. The Risk Factors for Virological Failure (RFVF) study compared 158 cases with...
16.
Murphy R, Marconi V, Gandhi R, Kuritzkes D, Sunpath H
PLoS One . 2017 Dec; 8(12). PMID: 29220839
[This corrects the article DOI: 10.1371/journal.pone.0044793.].
17.
Ngcapu S, Theys K, Libin P, Marconi V, Sunpath H, Ndungu T, et al.
Viruses . 2017 Nov; 9(11). PMID: 29117130
The South African national treatment programme includes nucleoside reverse transcriptase inhibitors (NRTIs) in both first and second line highly active antiretroviral therapy regimens. Mutations in the RNase H domain have...
18.
Murphy R, Court R, Maartens G, Sunpath H
AIDS Res Hum Retroviruses . 2017 Aug; 33(12):1181-1184. PMID: 28793781
The delay between first-line antiretroviral therapy (ART) failure and initiation of second-line ART in resource-limited settings can be prolonged. Increasing evidence links delayed antiretroviral switch with increased risk for opportunistic...
19.
Siedner M, Bwana M, Moosa M, Paul M, Pillay S, McCluskey S, et al.
HIV Clin Trials . 2017 Jul; 18(4):149-155. PMID: 28720039
Background: In sub-Saharan Africa, rates of sustained HIV virologic suppression remain below international goals. HIV resistance testing, while common in resource-rich settings, has not gained traction due to concerns about...
20.
Rhee S, Varghese V, Holmes S, van Zyl G, Steegen K, Boyd M, et al.
EBioMedicine . 2017 Apr; 18:225-235. PMID: 28365230
Tenofovir disoproxil fumarate (TDF) genotypic resistance defined by K65R/N and/or K70E/Q/G occurs in 20% to 60% of individuals with virological failure (VF) on a WHO-recommended TDF-containing first-line regimen. However, the...