Henri Leinonen
Overview
Explore the profile of Henri Leinonen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
33
Citations
560
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Montaser A, Gao F, Peters D, Vainionpaa K, Zhibin N, Skowronska-Krawczyk D, et al.
Mol Cell Proteomics
. 2024 Oct;
23(11):100855.
PMID: 39389360
Inherited retinal degenerations (IRDs) are a leading cause of blindness among the population of young people in the developed world. Approximately half of IRDs initially manifest as gradual loss of...
2.
Pazur E, Kalatanova A, Tasker N, Vainionpaa K, Leinonen H, Wipf P
ACS Med Chem Lett
. 2024 Jul;
15(7):1049-1056.
PMID: 39015263
Iso-dimethyltryptamine (isoDMT) analogues with heterocyclic substitutions at the indole C(3) were prepared in a hydrogen autotransfer alkylation and tested in combination with natural and unnatural clavine alkaloids in a model...
3.
Leinonen H, Zhang J, Occelli L, Seemab U, Choi E, L P Marinho L, et al.
Nat Commun
. 2024 Jul;
15(1):5943.
PMID: 39009597
Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology regardless of the underlying genetic lesion are desirable due to the diversity of...
4.
Ala-Nisula T, Halmetoja R, Leinonen H, Kurkela M, Lipponen H, Sakko S, et al.
Pflugers Arch
. 2024 Feb;
476(9):1339-1351.
PMID: 38396259
Transmembrane prolyl 4-hydroxylase (P4H-TM) is an enigmatic enzyme whose cellular function and primary substrate remain to be identified. Its loss-of-function mutations cause a severe neurological HIDEA syndrome with hypotonia, intellectual...
5.
Gao J, Leinonen H, Wang E, Ding M, Perry G, Palczewski K, et al.
J Alzheimers Dis
. 2023 Dec;
97(2):927-937.
PMID: 38143367
Background: Increasing evidence has highlighted retinal impairments in neurodegenerative diseases. Dominant mutations in TAR DNA-binding protein 43 (TDP-43) cause amyotrophic lateral sclerosis (ALS), and the accumulation of TDP-43 in the...
6.
Luu J, Saadane A, Leinonen H, Choi E, Gao F, Lewandowski D, et al.
Proc Natl Acad Sci U S A
. 2023 May;
120(19):e2221045120.
PMID: 37126699
Chronic, progressive retinal diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa, arise from genetic and environmental perturbations of cellular and tissue homeostasis. These disruptions accumulate with...
7.
Leinonen H, Zhou T, Ballios B, Kauppinen A, Fu Z
Front Neurosci
. 2022 Dec;
16:1102385.
PMID: 36532281
No abstract available.
8.
Huh C, Leinonen H, Nakayama T, Tomasello J, Zhang J, Zeitoun J, et al.
Curr Biol
. 2022 Sep;
32(20):4538-4546.e5.
PMID: 36152631
Despite the recent emergence of multiple cellular and molecular strategies to restore vision in retinal disorders, it remains unclear to what extent central visual circuits can recover when retinal defects...
9.
Leinonen H, Lyon D, Palczewski K, Foik A
eNeuro
. 2022 Jun;
9(3).
PMID: 35701168
Inherited retinal degenerative diseases are a prominent cause of blindness. Although mutations causing death of photoreceptors are mostly known, the pathophysiology downstream in the inner retina and along the visual...
10.
Choi E, Suh S, Foik A, Leinonen H, Newby G, Gao X, et al.
Nat Commun
. 2022 Apr;
13(1):1830.
PMID: 35383196
Leber congenital amaurosis (LCA) is the most common cause of inherited retinal degeneration in children. LCA patients with RPE65 mutations show accelerated cone photoreceptor dysfunction and death, resulting in early...