Henk Tjebbe vanderLeest
Overview
Explore the profile of Henk Tjebbe vanderLeest including associated specialties, affiliations and a list of published articles.
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9
Citations
487
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Recent Articles
1.
Hu K, Meijer J, Shea S, vanderLeest H, Pittman-Polletta B, Houben T, et al.
PLoS One
. 2012 Nov;
7(11):e48927.
PMID: 23185285
The mammalian central circadian pacemaker (the suprachiasmatic nucleus, SCN) contains thousands of neurons that are coupled through a complex network of interactions. In addition to the established role of the...
2.
van Oosterhout F, Fisher S, van Diepen H, Watson T, Houben T, vanderLeest H, et al.
Curr Biol
. 2012 Jul;
22(15):1397-402.
PMID: 22771039
The change in irradiance at dawn and dusk provides the primary cue for the entrainment of the mammalian circadian pacemaker. Irradiance detection has been ascribed largely to melanopsin-based phototransduction [1-5]....
3.
van Oosterhout F, Lucassen E, Houben T, vanderLeest H, Antle M, Meijer J
PLoS One
. 2012 Jul;
7(6):e39693.
PMID: 22761873
Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at the base of the hypothalamus. While light effects on the SCN are well established, little is known...
4.
Farajnia S, Michel S, Deboer T, vanderLeest H, Houben T, Rohling J, et al.
J Neurosci
. 2012 Apr;
32(17):5891-9.
PMID: 22539850
Aging is associated with a deterioration of daily (circadian) rhythms in physiology and behavior. Deficits in the function of the central circadian pacemaker in the suprachiasmatic nucleus (SCN) have been...
5.
Rohling J, vanderLeest H, Michel S, Vansteensel M, Meijer J
PLoS One
. 2011 Oct;
6(9):e25437.
PMID: 21966529
The circadian pacemaker of the suprachiasmatic nuclei (SCN) contains a major pacemaker for 24 h rhythms that is synchronized to the external light-dark cycle. In response to a shift in...
6.
vanderLeest H, Vansteensel M, Duindam H, Michel S, Meijer J
Chronobiol Int
. 2009 Sep;
26(6):1075-89.
PMID: 19731107
The mammalian circadian clock, located in the suprachiasmatic nucleus (SCN) of the hypothalamus, drives daily rhythms in behavioral, physiological, and endocrine functions. The SCN has a genetic basis for rhythm...
7.
vanderLeest H, Rohling J, Michel S, Meijer J
PLoS One
. 2009 Mar;
4(3):e4976.
PMID: 19305510
Background: In mammals, a major circadian pacemaker that drives daily rhythms is located in the suprachiasmatic nuclei (SCN), at the base of the hypothalamus. The SCN receive direct light input...
8.
vanderLeest H, Houben T, Michel S, Deboer T, Albus H, Vansteensel M, et al.
Curr Biol
. 2007 Feb;
17(5):468-73.
PMID: 17320387
The circadian pacemaker of the suprachiasmatic nucleus (SCN) functions as a seasonal clock through its ability to encode day length [1-6]. To investigate the mechanism by which SCN neurons code...
9.
Schaap J, Albus H, vanderLeest H, Eilers P, Detari L, Meijer J
Proc Natl Acad Sci U S A
. 2003 Dec;
100(26):15994-9.
PMID: 14671328
Circadian rhythms in neuronal ensemble, subpopulations, and single unit activity were recorded in the suprachiasmatic nuclei (SCN) of rat hypothalamic slices. Decomposition of the ensemble pattern revealed that neuronal subpopulations...