Hengjun Huang
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Explore the profile of Hengjun Huang including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
40
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Recent Articles
1.
Wu Y, Qian C, Huang H
Entropy (Basel)
. 2024 Jul;
26(7).
PMID: 39056897
Accurate prediction of air quality is crucial for assessing the state of the atmospheric environment, especially considering the nonlinearity, volatility, and abrupt changes in air quality data. This paper introduces...
2.
Zhang R, Wang D, Ruan G, Wang R, Li Y, Chen W, et al.
Development
. 2023 Dec;
151(2).
PMID: 38095286
The spliceosome, a multi-megadalton ribonucleoprotein complex, is essential for pre-mRNA splicing in the nucleus and ensuring genomic stability. Its precise and dynamic assembly is pivotal for its function. Spliceosome malfunctions...
3.
Li Y, Ruan G, Chen W, Huang H, Zhang R, Wang J, et al.
FEBS Lett
. 2023 May;
597(13):1748-1760.
PMID: 37171241
Naïve B cells become activated and differentiate into antibody-secreting plasma cells (PCs) when encountering antigens. Here, we reveal that the WW domain-containing adapter protein with coiled-coil (Wac), which is important...
4.
Huang H, Li Y, Zhang G, Ruan G, Zhu Z, Chen W, et al.
Nat Commun
. 2023 Mar;
14(1):1731.
PMID: 36997512
The T cell-dependent (TD) antibody response involves the generation of high affinity, immunoglobulin heavy chain class-switched antibodies that are generated through germinal center (GC) response. This process is controlled by...
5.
Chen W, Li Y, Ruan G, Huang H, Zhang R, Wang J, et al.
Cell Rep
. 2022 Nov;
41(8):111687.
PMID: 36417848
Adenosine deaminase acting on RNA-1 (ADAR1) is a ubiquitously expressed RNA deaminase catalyzing adenosine-to-inosine editing to prevent hyperactivated cytosolic double-stranded RNA (dsRNA) response mediated by MDA5. Here, we demonstrate that...
6.
Li Y, Ruan G, Chen W, Huang H, Zhang R, Wang J, et al.
J Immunol
. 2022 Aug;
209(6):1071-1082.
PMID: 35977796
Adenosine deaminase acting on RNA (ADAR)1 is the principal enzyme for adenosine-to-inosine editing, an RNA modification-avoiding cytosolic nucleic acid sensor's activation triggered by endogenous dsRNAs. Two ADAR1 isoforms exist in...
7.
Wang W, Huang H, Jiang H, Tian C, Tang Y, Gan D, et al.
Int J Mol Sci
. 2022 Jun;
23(12).
PMID: 35743028
The 5-methylcytosine (m5C) modification on an mRNA molecule is deposited by Nsun2 and its paralog Nsun6. While the physiological functions of Nsun2 have been carefully studied using gene knockout (KO)...
8.
Huang H, Zhang G, Ruan G, Li Y, Chen W, Zou J, et al.
J Immunol
. 2022 Apr;
208(8):1924-1936.
PMID: 35365563
The germinal center (GC) response is essential for generating memory B and long-lived Ab-secreting plasma cells during the T cell-dependent immune response. In the GC, signals via the BCR and...
9.
Ruan G, Li Y, Chen W, Huang H, Zhang R, Chen C, et al.
Cell Rep
. 2022 Feb;
38(6):110338.
PMID: 35139388
The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and tumorigenesis. However, the physiological...