Helmut Segner
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Explore the profile of Helmut Segner including associated specialties, affiliations and a list of published articles.
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151
Citations
1538
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Recent Articles
11.
Bailey C, Strepparava N, Ros A, Wahli T, Schmidt-Posthaus H, Segner H, et al.
J Anim Ecol
. 2021 Jun;
90(11):2573-2593.
PMID: 34165799
Heterogeneity in immunity occurs across numerous disease systems with individuals from the same population having diverse disease outcomes. Proliferative kidney disease (PKD) caused by Tetracapsuloides bryosalmonae, is a persistent parasitic...
12.
Werner I, Schneeweiss A, Segner H, Junghans M
Toxics
. 2021 Apr;
9(4).
PMID: 33917877
This study assessed the acute and chronic risk of pesticides, singly and as mixtures, for fish using comprehensive chemical data of four monitoring studies conducted in small- and medium-sized streams...
13.
Rehberger K, Escher B, Scheidegger A, Werner I, Segner H
Sci Rep
. 2021 Feb;
11(1):3167.
PMID: 33542403
A wide variety of environmental contaminants has been shown to disrupt immune functions of fish and may compromise their defense capability against pathogens. Immunotoxic effects, however, are rarely considered in...
14.
Tschirren L, Bachmann D, Guler A, Blaser O, Rhyner N, Seitz A, et al.
Animals (Basel)
. 2021 Jan;
11(1).
PMID: 33440704
Welfare in animal husbandry includes considerations of biology, ethics, ecology, law and economics. These diverse aspects must be translated into common quantifiable parameters and applicable methods to objectively assess welfare...
15.
Muller A, Markert N, Leser K, Kampfer D, Schiwy S, Riegraf C, et al.
Aquat Toxicol
. 2020 Dec;
231:105719.
PMID: 33360234
Numerous environmental pollutants have the potential to accumulate in sediments, and among them are endocrine-disrupting chemicals (EDCs). It is well documented that water-borne exposure concentrations of some potent EDCs, more...
16.
Kernen L, Rieder J, Duus A, Holbech H, Segner H, Bailey C
J Exp Zool A Ecol Integr Physiol
. 2020 Dec;
333(10):805-819.
PMID: 33306886
The thymus is present in all gnathostome vertebrates and is an essential organ for the adaptive immune system via the generation of functional mature T-cells. Over the life span of...
17.
Kropf C, Begnaud F, Gimeno S, Berthaud F, Debonneville C, Segner H
Environ Toxicol Chem
. 2020 Sep;
39(12):2396-2408.
PMID: 32915480
In vitro metabolic stability assays using rainbow trout (Oncorhynchus mykiss) isolated hepatocytes (RT-HEP) or hepatic S9 fractions (RT-S9) were introduced to provide biotransformation rate data for the assessment of chemical...
18.
Song J, Casanova-Nakayama A, Moller A, Kitamura S, Nakayama K, Segner H
Int J Mol Sci
. 2020 Sep;
21(17).
PMID: 32878328
The arylhydrocarbon receptor (AhR) is an important signaling pathway in the immune system of mammals. In addition to its physiological functions, the receptor mediates the immunotoxic actions of a diverse...
19.
Bailey C, Segner H, Wahli T, Tafalla C
Front Immunol
. 2020 Jun;
11:1093.
PMID: 32582181
Proliferative kidney disease (PKD) caused by the myxozoan parasite is one of the most serious infectious diseases negatively impacting farmed and wild salmonids throughout Europe and North America. PKD pathogenesis...
20.
Chen J, Chen M, Fang C, Zheng R, Jiang Y, Zhang Y, et al.
Mar Pollut Bull
. 2020 Jun;
158:111349.
PMID: 32573451
Microplastic (MP) pollution is an emerging contaminant in aquatic environments worldwide. Nonetheless, the developmental toxicity of MPs in the early life stages of fish and the mechanisms involved are not...