Helmut K G Machulla
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Explore the profile of Helmut K G Machulla including associated specialties, affiliations and a list of published articles.
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9
Citations
62
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Recent Articles
1.
Stein J, Machulla H, Deschner J, Fickl S, Jockel-Schneider Y, Tamm M, et al.
Clin Oral Investig
. 2015 Aug;
20(4):703-10.
PMID: 26303647
Objective: Human leukocyte antigens (HLA) have been associated with periodontitis. Previous studies revealed HLA-A9 and HLA-B15 as potential susceptibility factors, while HLA-A2 and HLA-B5 might have protective effects. The aim...
2.
Reichert S, Altermann W, Stein J, Schaller H, Machulla H, Schulz S
J Periodontol
. 2012 Mar;
84(1):100-9.
PMID: 22443520
Background: Human leukocyte antigens (HLAs) are a basic precondition to induce the immune response to pathogens. Therefore, this study evaluates associations among periodontitis, five key periodontopathic bacteria, and HLAs to...
3.
Reichert S, Machulla H, Klapproth J, Zimmermann U, Reichert Y, Glaser C, et al.
J Periodontol
. 2008 Aug;
79(8):1434-43.
PMID: 18672993
Background: The gene polymorphisms interferon-gamma (IFN-gamma) 874 T/A and interleukin (IL)-12 1188 A/C have been associated with the altered production of cytokines. Therefore, they might be indicative of the occurrence...
4.
Schulz S, Machulla H, Altermann W, Klapproth J, Zimmermann U, Glaser C, et al.
J Clin Periodontol
. 2008 Mar;
35(6):493-500.
PMID: 18363738
Aim: Tumour necrosis factor alpha (TNFalpha) plays an important role in the pathogenesis of periodontitis. TNFalpha production is influenced by gene polymorphisms. The aim of this study was to evaluate...
5.
Stein J, Machulla H, Smeets R, Lampert F, Reichert S
J Clin Periodontol
. 2008 Jan;
35(3):183-92.
PMID: 18190553
Aim: Multiple studies have reported associations between periodontitis and particular human leukocyte antigens (HLA). Because associations are inconsistent, we conducted a systematic literature review and a meta-analysis focusing on Caucasian...
6.
Reichert S, Stein J, Fuchs C, John V, Schaller H, Machulla H
J Clin Periodontol
. 2007 May;
34(6):492-8.
PMID: 17509091
Aim: The aim of this study was to evaluate common human leucocyte antigen (HLA) associations in patients with juvenile idiopathic arthritis (N=110), in patients with generalized aggressive periodontitis (N=50) and...
7.
Reichert S, Machulla H, Fuchs C, John V, Schaller H, Stein J
J Clin Periodontol
. 2006 Apr;
33(5):317-23.
PMID: 16634951
Aim: The aim was to compare the prevalence of periodontal conditions in patients with juvenile idiopathic arthritis (JIA) (n=78, age 14.4 years) with those revealed in a healthy control group...
8.
Machulla H, Steinborn F, Tschigrjai M, Langner J, Rainov N
Cancer Epidemiol Biomarkers Prev
. 2003 Dec;
12(12):1438-42.
PMID: 14693734
The expression of human leukocyte antigen (HLA) alleles plays an important role in the development and recurrence of benign and malignant diseases. Association of single HLA alleles or haplotypes with...
9.
Matthews V, Witt C, French M, Machulla H, de la Concha E, Cheong K, et al.
Hum Immunol
. 2002 Apr;
63(5):424-33.
PMID: 11975987
This study investigates the hypothesis that alternative alleles of one or more genes in the central major histocompatibility complex (MHC) predispose carriers to IgA deficiency (IgAD) or IgA Nephropathy (IgAN)....