Helga Schinkel
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Explore the profile of Helga Schinkel including associated specialties, affiliations and a list of published articles.
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16
Citations
160
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Recent Articles
1.
Nolke G, Chudobova I, Houdelet M, Volke D, Lusso M, Frederick J, et al.
Plant Direct
. 2021 Jun;
5(5):e00329.
PMID: 34095742
Traditional breeding and molecular approaches have been used to develop tobacco varieties with reduced nicotine and secondary alkaloid levels. However, available low-alkaloid tobacco varieties have impaired leaf quality likely due...
2.
Schiermeyer A, Schneider K, Kirchhoff J, Schmelter T, Koch N, Jiang K, et al.
Plant Direct
. 2019 Jul;
3(7):e00153.
PMID: 31360827
Targeted integration of recombinant DNA fragments into plant genomes by DNA double-strand break (DSB) repair mechanisms has become a powerful tool for precision engineering of crops. However, many targeting platforms...
3.
Nolke G, Volke D, Chudobova I, Houdelet M, Lusso M, Frederick J, et al.
Plant Direct
. 2019 Jun;
2(7):e00077.
PMID: 31245740
The development of low-alkaloid (LA) tobacco varieties is an important target in the tobacco breeding industry. However, LA Burley 21 plants, in which the and loci controlling nicotine biosynthesis are...
4.
Hogberg P, Hogbom L, Schinkel H, Hogberg M, Johannisson C, Wallmark H
Oecologia
. 2017 Mar;
108(2):207-214.
PMID: 28307831
N natural abundances of soil total N, roots and mycorrhizas were studied in surface soil profiles in coniferous and broadleaved forests along a transect from central to northern Europe. Under...
5.
Schinkel H, Schillberg S
Plant Cell Rep
. 2016 May;
35(7):1487-91.
PMID: 27146974
Genome editing is a revolutionary technology in molecular biology. While scientists are fascinated with the unlimited possibilities provided by directed and controlled changes in DNA in eukaryotes and have eagerly...
6.
Addai-Mensah O, Seidel M, Amidu N, Maskus D, Kapelski S, Breuer G, et al.
Malar J
. 2016 Feb;
15:65.
PMID: 26850066
Background: Malaria still represents a major cause of morbidity and mortality predominantly in several developing countries, and remains a priority in many public health programmes. Despite the enormous gains made...
7.
Schneider K, Schiermeyer A, Dolls A, Koch N, Herwartz D, Kirchhoff J, et al.
Plant Biotechnol J
. 2015 Oct;
14(4):1151-60.
PMID: 26426390
Genome modification by homology-directed repair (HDR) is an attractive tool for the controlled genetic manipulation of plants. Here, we report the HDR-mediated gene exchange of expression cassettes in tobacco BY-2...
8.
Spiegel H, Schinkel H, Kastilan R, Dahm P, Boes A, Scheuermayer M, et al.
Biotechnol Bioeng
. 2014 Oct;
112(4):659-67.
PMID: 25335451
We demonstrated the successful optimization of a recombinant multi-subunit malaria vaccine candidate protein for production in the methylotrophic yeast Pichia pastoris by the identification and subsequent removal of two protease...
9.
Feller T, Thom P, Koch N, Spiegel H, Addai-Mensah O, Fischer R, et al.
PLoS One
. 2013 Nov;
8(11):e79920.
PMID: 24278216
Pf38 is a surface protein of the malarial parasite Plasmodium falciparum. In this study, we produced and purified recombinant Pf38 and a fusion protein composed of red fluorescent protein and...
10.
Kirchhoff J, Raven N, Boes A, Roberts J, Russell S, Treffenfeldt W, et al.
Plant Biotechnol J
. 2012 Jul;
10(8):936-44.
PMID: 22758383
Plant cell suspension cultures can be used for the production of recombinant pharmaceutical proteins, but their potential is limited by modest production levels that may be unstable over long culture...