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Helene Highbarger

Explore the profile of Helene Highbarger including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 209
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Recent Articles
1.
Singh K, Rubenstein K, Callier V, Shaw-Saliba K, Rupert A, Dewar R, et al.
J Infect Dis . 2024 Apr; 230(3):624-634. PMID: 38657001
Background: Although antivirals remain important for the treatment COVID-19, methods to assess treatment efficacy are lacking. Here, we investigated the impact of remdesivir on viral dynamics and their contribution to...
2.
Aggarwal N, Nordwall J, Braun D, Chung L, Coslet J, Der T, et al.
Clin Infect Dis . 2024 Feb; 78(6):1490-1503. PMID: 38376212
Background: Persistent mortality in adults hospitalized due to acute COVID-19 justifies pursuit of disease mechanisms and potential therapies. The aim was to evaluate which virus and host response factors were...
3.
Rogers A, Wentworth D, Phillips A, Shaw-Saliba K, Dewar R, Aggarwal N, et al.
Ann Intern Med . 2022 Aug; 175(10):1401-1410. PMID: 36037469
Background: Levels of plasma SARS-CoV-2 nucleocapsid (N) antigen may be an important biomarker in patients with COVID-19 and enhance our understanding of the pathogenesis of COVID-19. Objective: To evaluate whether...
4.
Lundgren J, Grund B, Barkauskas C, Holland T, Gottlieb R, Sandkovsky U, et al.
Ann Intern Med . 2021 Dec; 175(2):234-243. PMID: 34928698
Background: In a randomized, placebo-controlled, clinical trial, bamlanivimab, a SARS-CoV-2-neutralizing monoclonal antibody, given in combination with remdesivir, did not improve outcomes among hospitalized patients with COVID-19 based on an early...
5.
Imamichi T, Bernbaum J, Laverdure S, Yang J, Chen Q, Highbarger H, et al.
J Virol . 2021 Sep; 95(23):e0132321. PMID: 34523971
Recently, a genome-wide association study using plasma HIV RNA from antiretroviral therapy-naive patients reported that 14 naturally occurring nonsynonymous single-nucleotide polymorphisms (SNPs) in HIV derived from antiretrovirus drug-naive patients were...
6.
Osinusi A, Meissner E, Lee Y, Bon D, Heytens L, Nelson A, et al.
JAMA . 2013 Aug; 310(8):804-11. PMID: 23982366
Importance: The efficacy of directly acting antiviral agents in interferon-free regimens for the treatment of chronic hepatitis C infections needs to be evaluated in different populations. Objective: To determine the...