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Helene Dumond

Explore the profile of Helene Dumond including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 379
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Recent Articles
1.
Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H
Steroids . 2023 Aug; 199:109285. PMID: 37543222
Sex-specific differences in brain organization and function are widely explored in multidisciplinary studies, ranging from sociology and biology to digital modelling. In addition, there is growing evidence that natural or...
2.
Hirtz A, Bailly Y, Rech F, Pierson J, Dumond H, Dubois-Pot-Schneider H
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430793
Glioblastoma (GBM) is the most common primary brain tumor in adults. Despite conventional treatment, consisting of a chirurgical resection followed by concomitant radio-chemotherapy, the 5-year survival rate is less than...
3.
Hirtz A, Lebourdais N, Thomassin M, Rech F, Dumond H, Dubois-Pot-Schneider H
Cancers (Basel) . 2022 Sep; 14(17). PMID: 36077653
Low-grade gliomas are rare primary brain tumors, which fatally evolve to anaplastic gliomas. The current treatment combines surgery, chemotherapy, and radiotherapy. If gender differences in the natural history of the...
4.
Hirtz A, Lebourdais N, Rech F, Bailly Y, Vaginay A, Smail-Tabbone M, et al.
Cells . 2021 Dec; 10(12). PMID: 34943948
Glioblastoma (GBM) is the most common brain tumor in adults, which is very aggressive, with a very poor prognosis that affects men twice as much as women, suggesting that female...
5.
Hirtz A, Rech F, Dubois-Pot-Schneider H, Dumond H
Int J Mol Sci . 2020 Dec; 21(23). PMID: 33266110
Astrocytomas and, in particular, their most severe form, glioblastoma, are the most aggressive primary brain tumors and those with the poorest vital prognosis. Standard treatment only slightly improves patient survival....
6.
Thiebaut C, Konan H, Guerquin M, Chesnel A, Livera G, Le Romancer M, et al.
Int J Mol Sci . 2020 Jun; 21(11). PMID: 32526980
Estrogen nuclear receptors, represented by the canonical forms ERα66 and ERβ1, are the main mediators of the estrogen-dependent pathophysiology in mammals. However, numerous isoforms have been identified, stimulating unconventional estrogen...
7.
Thiebaut C, Chesnel A, Merlin J, Chesnel M, Leroux A, Harle A, et al.
Int J Mol Sci . 2019 Jun; 20(11). PMID: 31146345
Breast cancer remains the major cause of cancer-induced morbidity and mortality in women. Among the different molecular subtypes, luminal tumors yet considered of good prognosis often develop acquired resistance to...
8.
Chamard-Jovenin C, Thiebaut C, Chesnel A, Bresso E, Morel C, Smail-Tabbone M, et al.
Front Endocrinol (Lausanne) . 2017 Nov; 8:272. PMID: 29109696
Fetal and neonatal exposure to long-chain alkylphenols has been suspected to promote breast developmental disorders and consequently to increase breast cancer risk. However, disease predisposition from developmental exposures remains unclear....
9.
Thiebaut C, Chamard-Jovenin C, Chesnel A, Morel C, Djermoune E, Boukhobza T, et al.
PLoS One . 2017 Mar; 12(3):e0173931. PMID: 28301550
Estrogen receptor alpha 36 (ERα36) is a variant of the canonical estrogen receptor alpha (ERα66), widely expressed in hormone sensitive cancer cells and whose high expression level correlates with a...
10.
Chamard-Jovenin C, Jung A, Chesnel A, Abecassis J, Flament S, Ledrappier S, et al.
BMC Syst Biol . 2015 Jun; 9:28. PMID: 26080803
Background: Estrogen receptor alpha36 (ERalpha36), a variant of estrogen receptor alpha (ER) is expressed in about half of breast tumors, independently of the [ER+]/[ER-] status. In vitro, ERalpha36 triggers mitogenic...