Helene Diemer
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Explore the profile of Helene Diemer including associated specialties, affiliations and a list of published articles.
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49
Citations
648
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Recent Articles
1.
Benazza R, Letissier L, Papadakos G, Thom J, Diemer H, Cotton G, et al.
Anal Chem
. 2025 Jan;
97(5):2639-2647.
PMID: 39889214
Even though mAbs have attracted the biggest interest in the development of therapeutic proteins, next-generation therapeutics such as single-domain antibodies (sdAb) are propelling increasing attention as new alternatives with appealing...
2.
Aubry L, Vitipon M, Hirschler A, Diemer H, Rabilloud T, Carapito C, et al.
Sci Rep
. 2025 Jan;
15(1):695.
PMID: 39753660
Pigment particles used in tattooing may exert long terms effect by releasing diffusible degradation products. In the present work, aqueous suspensions of the organic orange diazo pigment PO13 were aged...
3.
Coliat P, Erb S, Diemer H, Karouby D, Martin T, Banerjee M, et al.
Sci Rep
. 2023 Dec;
13(1):21875.
PMID: 38072852
Pneumatic transportation systems (PTS) were recently proposed as a method to carry ready-for-injection diluted monoclonal antibodies (mAbs) from the pharmacy to the bedside of patients. This method reduces transportation time...
4.
Koutsopetras I, Vaur V, Benazza R, Diemer H, Sornay C, Ersoy Y, et al.
Chemistry
. 2023 Dec;
30(14):e202303242.
PMID: 38050774
The chemical bioconjugation of proteins has seen tremendous applications in the past decades, with the booming of antibody-drug conjugates and their use in oncology. While genetic engineering has permitted to...
5.
Beaumal C, Desligniere E, Diemer H, Carapito C, Cianferani S, Hernandez-Alba O
Anal Bioanal Chem
. 2023 Nov;
416(2):519-532.
PMID: 38008785
Antibody-drug conjugates (ADCs) are highly complex proteins mainly due to the structural microvariability of the mAb, along with the additional heterogeneity afforded by the bioconjugation process. Top-down (TD) and middle-down...
6.
Butre C, DAtri V, Diemer H, Colas O, Wagner E, Beck A, et al.
Molecules
. 2023 Mar;
28(6).
PMID: 36985827
In the quest to market increasingly safer and more potent biotherapeutic proteins, the concept of the multi-attribute method (MAM) has emerged from biopharmaceutical companies to boost the quality-by-design process development....
7.
Desligniere E, Diemer H, Erb S, Coliat P, Pivot X, Detappe A, et al.
Front Biosci (Landmark Ed)
. 2022 Nov;
27(10):290.
PMID: 36336868
Background: Native mass spectrometry (nMS) approaches appear attractive to complement bottom-up strategies traditionally used in biopharmaceutical industries thanks to their quite straightforward and rapid workflows, especially through online hyphenation of...
8.
Torres A, Collin-Faure V, Diemer H, Moriscot C, Fenel D, Gallet B, et al.
Nanomaterials (Basel)
. 2022 May;
12(9).
PMID: 35564134
Synthetic amorphous silica (SAS) is a nanomaterial used in a wide variety of applications, including the use as a food additive. Two types of SAS are commonly employed as a...
9.
Cavazza C, Collin-Faure V, Perard J, Diemer H, Cianferani S, Rabilloud T, et al.
J Proteomics
. 2021 Oct;
250:104389.
PMID: 34601154
Some carboxydotrophs like Rhodospirillum rubrum are able to grow with CO as their sole source of energy using a Carbone monoxide dehydrogenase (CODH) and an Energy conserving hydrogenase (ECH) to...
10.
Desligniere E, Botzanowski T, Diemer H, Cooper-Shepherd D, Wagner-Rousset E, Colas O, et al.
J Am Soc Mass Spectrom
. 2021 Aug;
32(10):2505-2512.
PMID: 34437803
Monoclonal antibodies (mAbs) have taken on an increasing importance for the treatment of various diseases, including cancers and immunological disorders. Disulfide bonds play a pivotal role in therapeutic antibody structure...