» Authors » Helene C Highbarger

Helene C Highbarger

Explore the profile of Helene C Highbarger including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 13
Citations 65
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Jensen T, Murray T, Grandits G, Jain M, Grund B, Shaw-Saliba K, et al.
Lancet Microbe . 2024 May; 5(6):e559-e569. PMID: 38815595
Background: Serial measurement of virological and immunological biomarkers in patients admitted to hospital with COVID-19 can give valuable insight into the pathogenic roles of viral replication and immune dysregulation. We...
2.
Jensen T, Grandits G, Jain M, Murray T, Grund B, Shaw-Saliba K, et al.
J Infect Dis . 2023 Nov; 229(3):671-679. PMID: 37948759
Background: Neutralizing monoclonal antibodies (nmAbs) failed to show clear benefit for hospitalized patients with coronavirus disease 2019 (COVID-19). Dynamics of virologic and immunologic biomarkers remain poorly understood. Methods: Participants enrolled...
3.
Dabitao D, Shaw-Saliba K, Konate D, Highbarger H, Lallemand P, Sanogo I, et al.
J Immunol Methods . 2023 May; 517:113488. PMID: 37179012
The levels of immune response to SARS-CoV-2 infection or vaccination are poorly understood in African populations and is complicated by cross-reactivity to endemic pathogens as well as differences in host...
4.
Huapaya J, Higgins J, Kanth S, Demirkale C, Gairhe S, Aboye E, et al.
J Infect Dis . 2023 Feb; 228(1):46-58. PMID: 36801946
Background: Data on cellular immune responses in persons with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection following vaccination are limited. The evaluation of these patients with SARS-CoV-2 breakthrough infections...
5.
Barkauskas C, Mylonakis E, Poulakou G, Young B, Vock D, Siegel L, et al.
Ann Intern Med . 2022 Aug; 175(9):1266-1274. PMID: 35939810
Background: Ensovibep (MP0420) is a designed ankyrin repeat protein, a novel class of engineered proteins, under investigation as a treatment of SARS-CoV-2 infection. Objective: To investigate if ensovibep, in addition...
6.
Yang J, Hao M, Khan M, Rehman M, Highbarger H, Chen Q, et al.
Viruses . 2021 Nov; 13(11). PMID: 34835137
We have recently reported that a recombinant HIV-1NL4.3 containing Met-to-Ile change at codon 50 of integrase (IN) (IN:M50I) exhibits suppression of the virus release below 0.5% of WT HIV, and...
7.
Cai C, Pinyakorn S, Kroon E, de Souza M, Colby D, Pankam T, et al.
Open Forum Infect Dis . 2020 Oct; 7(9):ofaa383. PMID: 33005700
Persistent viral activity may cause enduring seropositivity and inflammation in treated people with HIV (PWH). We compared inflammatory biomarkers between early treated PWH who remained seronegative or seroconverted and found...
8.
Huang D, Raley C, Jiang M, Zheng X, Liang D, Rehman M, et al.
J Data Mining Genomics Proteomics . 2016 Mar; 7(1). PMID: 26949565
Development of HIV-1 drug resistance mutations (HDRMs) is one of the major reasons for the clinical failure of antiretroviral therapy. Treatment success rates can be improved by applying personalized anti-HIV...
9.
Dlamini J, Hu Z, Ledwaba J, Morris L, Maldarelli F, Dewar R, et al.
J Acquir Immune Defic Syndr . 2011 Jun; 58(3):304-8. PMID: 21694608
Nonnucleoside reverse transcriptase inhibitor-drug resistance mutations (DRM) are increasingly reported in Africans failing their first antiretroviral regimen. The Phidisa II trial randomized treatment-naive participants to lopinavir/ritonavir or efavirenz with stavudine...
10.
Dlamini J, Hu Z, Somaroo H, Highbarger H, Follmann D, Dewar R, et al.
Pharmacotherapy . 2011 Feb; 31(2):158-63. PMID: 21275494
Study Objective: To evaluate the effect of a previous single dose of nevirapine given to prevent mother-to-child transmission of human immunodeficiency virus (HIV) on virologic and immunologic measures after months...