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Helena Lee

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Articles 59
Citations 1144
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Recent Articles
11.
Lee H, Wilson D, Bunting K, Kotecha D, Jackson T
Ageing Res Rev . 2023 Jan; 86:101860. PMID: 36682465
The geroscience hypothesis proposes biological hallmarks of ageing are modifiable. Increasing evidence supports targeting these hallmarks with therapeutics could prevent and ameliorate age-related conditions - collectively termed "geroprotector drugs". Cellular...
12.
Lee H, Thein O, Muneer T
BMJ Case Rep . 2022 Nov; 15(11). PMID: 36379633
During the COVID-19 pandemic, it was recognised that SARS-CoV-2 can cause multisystem illness. Non-respiratory complications observed early in the pandemic were haematological in nature. A rare but serious haematological complication...
13.
Zemedikun D, Lee H, Nirantharakumar K, Raza K, Chandan J, Lord J, et al.
Arthritis Res Ther . 2022 Oct; 24(1):231. PMID: 36229868
Background: Osteoarthritis (OA) is a common chronic condition but its association with other chronic conditions and mortality is largely unknown. This study aimed to use latent class analysis (LCA) of...
14.
Lee H, Purohit R, Sheth V, Maconachie G, Tu Z, Thomas M, et al.
Am J Ophthalmol . 2022 Sep; 245:202-211. PMID: 36084688
Meeting Presentation: Presented at the 2016 Association for Research in Vision and Ophthalmology meeting and at the 2015 British Isles Paediatric, Ophthalmology and Strabismus Association meeting. Purpose: To investigate the...
15.
Rennie K, Alagendran R, Lee H, Griffiths H, Self J
BMC Ophthalmol . 2022 Jun; 22(1):268. PMID: 35718783
Purpose: Nystagmus is a disorder characterized by uncontrolled, rhythmic oscillations of the eyes. It often causes reduced visual function beyond reduced visual acuity alone. There is a paucity of literature...
16.
Holmqvist K, Orbom S, Hooge I, Niehorster D, Alexander R, Andersson R, et al.
Behav Res Methods . 2022 Apr; 55(1):364-416. PMID: 35384605
In this paper, we present a review of how the various aspects of any study using an eye tracker (such as the instrument, methodology, environment, participant, etc.) affect the quality...
17.
Lin S, Sanchez-Bretano A, Leslie J, Williams K, Lee H, Thomas N, et al.
NPJ Genom Med . 2022 Jan; 7(1):2. PMID: 35027574
Oculocutaneous albinism type 1 (OCA1) is caused by pathogenic variants in the TYR (tyrosinase) gene which encodes the critical and rate-limiting enzyme in melanin synthesis. It is the most common...
18.
Nicholson R, Osborne D, Fairhead L, Beed L, Hill C, Lee H
Eye (Lond) . 2022 Jan; 36(5):963-968. PMID: 35001092
Background: Down syndrome is a common multigene, multisystem disorder associated with abnormalities of visual function and characteristic changes in the majority of tissues in the eye. Historic descriptions of macular...
19.
Pacia C, Holloway J, Gunning C, Lee H
Rev J Autism Dev Disord . 2021 Apr; 9(2):208-234. PMID: 33821200
Social communication deficits are a core symptom of autism spectrum disorder (ASD). The present paper reviews 54 studies evaluating social communication interventions delivered by parents and siblings to children with...
20.
Lynn S, Johnston D, Scott J, Munday R, Desai R, Keeling E, et al.
Cells . 2021 Mar; 10(2). PMID: 33671133
Alzheimer's disease-associated amyloid beta (Aβ) proteins accumulate in the outer retina with increasing age and in eyes of age-related macular degeneration (AMD) patients. To study Aβ-induced retinopathy, wild-type mice were...