Helen Tremlett
Overview
Explore the profile of Helen Tremlett including associated specialties, affiliations and a list of published articles.
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219
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5068
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Recent Articles
1.
Karim M, Hossain M, Ng H, Zhu F, Frank H, Tremlett H
Pharmacoepidemiol Drug Saf
. 2025 Feb;
34(2):e70112.
PMID: 39901338
Purpose: Given the historical use of limited confounders in multiple sclerosis (MS) studies utilizing administrative health data, this brief report evaluates the impact of incorporating high-dimensional proxy information on confounder...
2.
Healthcare use is elevated two decades before a first demyelinating event and differs by age and sex
Tremlett H, Zhu F, Everett K, Asaf A, Manouchehrinia A, Li P, et al.
Ann Clin Transl Neurol
. 2025 Jan;
12(2):415-432.
PMID: 39887956
Objective: Elevated healthcare use before multiple sclerosis (MS) onset suggests earlier opportunity to identify MS. Yet their timing and sociodemographic effects are unclear. We examined rates of healthcare use (and...
3.
Akmatov M, Graf J, Kohring C, Ellenberger D, Batzing J, Tremlett H, et al.
JAMA Netw Open
. 2024 Dec;
7(12):e2452652.
PMID: 39729316
Importance: A growing body of literature suggests the presence of a prodromal period with nonspecific signs and symptoms before onset of multiple sclerosis (MS). Objective: To systematically assess diseases and...
4.
Yusuf F, Karim M, Gustafson P, Sutherland J, Zhu F, Zhao Y, et al.
Ann Epidemiol
. 2024 Dec;
101():67-73.
PMID: 39701480
Background: Studies suggest that depression/anxiety form part of the multiple sclerosis (MS) prodrome. However, several biases have not been addressed. We re-examined this association after correcting for: (i) misclassification of...
5.
Bergeron-Vitez H, Yusuf F, Zhu F, Zhao Y, Evans C, Fisk J, et al.
Mult Scler Relat Disord
. 2024 Dec;
93:106167.
PMID: 39616772
Background: Before disease onset, multiple sclerosis (MS) persons fill more prescriptions than controls, including for pain. However, knowledge regarding neuropathic pain-related medications is lacking OBJECTIVE: Compare odds of anticonvulsant/gabapentinoid prescriptions...
6.
Jette S, de Schaetzen C, Tsai C, Tremlett H
Mult Scler Relat Disord
. 2024 Nov;
92:106151.
PMID: 39586156
Background: The gut microbiome is a potential therapeutic target for multiple sclerosis (MS), yet its association with disease activity remains unclear. We systematically reviewed the literature to investigate the relationship...
7.
Frank H, Chao M, Tremlett H, Marrie R, Lix L, McKay K, et al.
Mult Scler Relat Disord
. 2024 Nov;
92:105943.
PMID: 39489083
Introduction: Multiple sclerosis (MS) has a high comorbidity burden. Despite known associations with adverse outcomes, a comprehensive evaluation of the specific associations between individual comorbidities and disability, treatment initiation, and...
8.
Graf J, Akmatov M, Meuth S, Tremlett H, Holstiege J
JAMA Neurol
. 2024 Sep;
81(10):1100-1102.
PMID: 39250144
No abstract available.
9.
Rotstein D, Freedman M, Konig A, Lee L, Luo J, Maxwell C, et al.
Mult Scler
. 2024 Sep;
30(10):1331-1340.
PMID: 39234853
Background: Prodromal phases are well recognized in many inflammatory and neurodegenerative diseases, including multiple sclerosis. We evaluated the possibility of a prodrome in aquaporin-4 antibody positive (AQP4+) neuromyelitis optica spectrum...
10.
Lin Q, Dorsett Y, Mirza A, Tremlett H, Piccio L, Longbrake E, et al.
Genome Med
. 2024 Jul;
16(1):94.
PMID: 39085949
Background: Previous studies have identified a diverse group of microbial taxa that differ between patients with multiple sclerosis (MS) and the healthy population. However, interpreting findings on MS-associated microbiota is...