Helen Ferreira
Overview
Explore the profile of Helen Ferreira including associated specialties, affiliations and a list of published articles.
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17
Citations
195
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Recent Articles
1.
Feitosa da Silva Barboza M, de Andrea Hacker M, Maria Sales A, Fontoura Rodrigues D, Pedrosa Marques D, Jose Ciryllo Silva Noya D, et al.
Front Immunol
. 2024 Jul;
15():1368460.
PMID: 39072336
Background: Leprosy reactions represent immunologically mediated episodes of acute inflammation that, if not diagnosed and treated promptly, can cause irreversible impairment of nerve function and permanent disabilities. A frequent type...
2.
Ferreira H, Leal-Calvo T, Mendes M, Avanzi C, Busso P, Benjak A, et al.
Front Cell Infect Microbiol
. 2022 Aug;
12:917282.
PMID: 35937686
Multidrug therapy (MDT) has been successfully used in the treatment of leprosy. However, although patients are cured after the completion of MDT, leprosy reactions, permanent disability, and occasional relapse/reinfection are...
3.
Leal Silveira Andrezo Rosa T, Mendes M, Linhares N, Rodrigues T, Dias A, Leal-Calvo T, et al.
Front Med (Lausanne)
. 2022 Jun;
9:899998.
PMID: 35733868
In leprosy patients, acute inflammatory episodes, known as erythema nodosum leprosum (ENL), are responsible for high morbidity and tissue damage that occur during the course of infection. In a previous...
4.
Ferreira H, Mendes M, de Mattos Barbosa M, de Oliveira E, Maria Sales A, Moraes M, et al.
Front Immunol
. 2021 Aug;
12:662307.
PMID: 34354699
The treatment of multibacillary cases of leprosy with multidrug therapy (MDT) comprises 12 doses of a combination of rifampicin, dapsone and clofazimine. Previous studies have described the immunological phenotypic pattern...
5.
da Silva T, Bittencourt T, de Oliveira A, Prata R, Menezes V, Ferreira H, et al.
Front Immunol
. 2020 Aug;
11:1493.
PMID: 32849508
In HIV-infected individuals, a paradoxical clinical deterioration may occur in preexisting leprosy when highly active antiretroviral therapy (HAART)-associated reversal reaction (RR) develops. Leprosy-HIV co-infected patients during HAART may present a...
6.
Pacheco F, Prata R, Brandao S, Ferreira H, Rodrigues T, Dos Santos J, et al.
Immunohorizons
. 2020 Feb;
4(2):47-56.
PMID: 32034084
Erythema nodosum leprosum (ENL) is an inflammatory complication in leprosy. Yet, the involvement of ENL neutrophils in the inflammatory response against remains poorly explored. Our primary aim was to investigate...
7.
Oliveira da Silva C, Dias A, Nery J, de Miranda Machado A, Ferreira H, Rodrigues T, et al.
PLoS Negl Trop Dis
. 2019 Sep;
13(9):e0007368.
PMID: 31504035
Up to 50% of patients with the multibacillary form of leprosy are expected to develop acute systemic inflammatory episodes known as type 2 reactions (T2R), thus aggravating their clinical status....
8.
de Mattos Barbosa M, Silva B, Assis T, Prata R, Ferreira H, Andrade P, et al.
Front Immunol
. 2018 Jun;
9:1223.
PMID: 29915584
Leprosy reactions are responsible for incapacities in leprosy and represent the major cause of permanent neuropathy. The identification of biomarkers able to identify patients more prone to develop reaction could...
9.
Mendes M, de Carvalho D, Porto Amadeu T, Silva B, Prata R, Oliveira da Silva C, et al.
J Infect Dis
. 2017 Dec;
216(12):1635-1643.
PMID: 29272525
Background: Leprosy, the leading infectious cause of disability worldwide, remains a major public health challenge in the most severely affected countries despite the sharp decline in new cases in recent...
10.
de Mattos Barbosa M, Prata R, Andrade P, Ferreira H, Silva B, Araujo da Paixao de Oliveira J, et al.
Microbes Infect
. 2017 Jul;
19(11):505-514.
PMID: 28684130
Our previous study has demonstrated that IL-10 may modulate both indoleamine 2,3-dioxygenase (IDO) and CD163 expression in lepromatous leprosy (LL) cells, favoring Mycobacterium leprae persistence through induction of regulatory pathways...