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Helen Eccleson

Explore the profile of Helen Eccleson including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 137
Followers 0
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Recent Articles
1.
Lewis G, Dodd S, Clayton D, Bedson E, Eccleson H, Schelbert E, et al.
Nat Med . 2021 Aug; 27(8):1477-1482. PMID: 34385704
In heart failure with preserved ejection fraction (HFpEF), the occurrence of myocardial fibrosis is associated with adverse outcome. Whether pirfenidone, an oral antifibrotic agent without hemodynamic effect, is efficacious and...
2.
Deja E, Roper L, Tume L, Dorling J, Gale C, Arch B, et al.
Pilot Feasibility Stud . 2021 Feb; 7(1):49. PMID: 33593416
Background: Routine measurement of gastric residual volume (GRV) to guide feeding in neonatal and paediatric intensive care is widespread. However, this practice is not evidence based and may cause harm....
3.
Gale C, Dorling J, Arch B, Woolfall K, Deja E, Roper L, et al.
Arch Dis Child Fetal Neonatal Ed . 2020 Oct; 106(3):292-297. PMID: 33127738
Background: Routine measurement of gastric residual volume to guide feeding is widespread in neonatal units but not supported by high-quality evidence. Outcome selection is critical to trial design. Objective: To...
4.
Dorling J, Tume L, Arch B, Woolfall K, Latten L, Roper L, et al.
BMJ Paediatr Open . 2020 Aug; 4(1):e000601. PMID: 32821858
Objective: Despite little evidence, the practice of routine gastric residual volume (GRV) measurement to guide enteral feeding in neonatal units is widespread. Due to increased interest in this practice, and...
5.
Tume L, Woolfall K, Arch B, Roper L, Deja E, Jones A, et al.
Health Technol Assess . 2020 May; 24(23):1-120. PMID: 32458797
Background: The routine measurement of gastric residual volume to guide the initiation and delivery of enteral feeding is widespread in paediatric intensive care and neonatal units, but has little underlying...
6.
Tume L, Arch B, Woolfall K, Roper L, Deja E, Jones A, et al.
JPEN J Parenter Enteral Nutr . 2020 Mar; 45(1):79-86. PMID: 32144809
Background: Choosing trial outcome measures is important. When outcomes are not clinically relevant or important to parents/patients, trial evidence is less likely to be implemented into practice. This study aimed...
7.
Tume L, Arch B, Woolfall K, Latten L, Deja E, Roper L, et al.
Pediatr Crit Care Med . 2019 Aug; 20(8):707-713. PMID: 31398180
Objectives: Despite little evidence, the practice of routine measurement of gastric residual volume to guide both the initiation and delivery of enteral feeding in PICUs is widespread internationally. In light...
8.
Lewis G, Schelbert E, Naish J, Bedson E, Dodd S, Eccleson H, et al.
Cardiovasc Drugs Ther . 2019 May; 33(4):461-470. PMID: 31069575
Background: The PIROUETTE (PIRfenidOne in patients with heart failUre and preserved lEfT venTricular Ejection fraction) trial is designed to evaluate the efficacy and safety of the anti-fibrotic pirfenidone in patients...
9.
Van Miert C, Fernandes R, Eccleson H, Bedson E, Lane S, Peak M, et al.
Trials . 2018 Nov; 19(1):627. PMID: 30428935
Background: Bronchiolitis is an acute lower respiratory infection which predominantly affects young children. Treatment for bronchiolitis is limited to supportive therapy. Nasal oxygen therapy is part of routine care, and...