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Heike Luise Pahl

Explore the profile of Heike Luise Pahl including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 25
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Recent Articles
1.
Staehle A, Peeken J, Vladimirov G, Hoeness M, Kovacs S, Karantzelis N, et al.
Leukemia . 2023 Jan; 37(4):919-923. PMID: 36709354
The transcription factor NFE2 is overexpressed in most patients with myeloproliferative neoplasms (MPN). Moreover, mutations in NFE2, found in a subset of MPN patients, strongly predispose for transformation to acute...
2.
Staehle H, Pahl H, Jutzi J
Biomolecules . 2021 Dec; 11(12). PMID: 34944554
Histone methylation tightly regulates chromatin accessibility, transcription, proliferation, and cell differentiation, and its perturbation contributes to oncogenic reprogramming of cells. In particular, many myeloid malignancies show evidence of epigenetic dysregulation....
3.
Bockelmann L, Basu T, Grunder A, Wang W, Breucker J, Kaiser S, et al.
Haematologica . 2020 Jun; 106(4):1158-1162. PMID: 32554556
No abstract available.
4.
Staehle H, Heinemann J, Gruender A, Omlor A, Pahl H, Jutzi J
PLoS One . 2020 Feb; 15(2):e0228362. PMID: 32017785
The histone demethylase JMJD1C is overexpressed in patients with myeloproliferative neoplasms (MPNs) and has been implicated in leukemic stem cell function of MLL-AF9 and HOXA9-driven leukemia. In the emerging field...
5.
Sies K, Spohr C, Grunder A, Todorova R, Uhl F, Huber J, et al.
Hemasphere . 2019 Nov; 3(2):e184. PMID: 31723823
No abstract available.
6.
Jutzi J, Basu T, Pellmann M, Kaiser S, Steinemann D, Sanders M, et al.
Blood . 2019 Feb; 133(16):1766-1777. PMID: 30755419
In acute myeloid leukemia (AML), acquired genetic aberrations carry prognostic implications and guide therapeutic decisions. Clinical algorithms have been improved by the incorporation of novel aberrations. Here, we report the...