Hee-Kap Kang
Overview
Explore the profile of Hee-Kap Kang including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
456
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0
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Recent Articles
1.
Lerret N, Li T, Wang J, Kang H, Wang S, Wang X, et al.
J Am Soc Nephrol
. 2015 Mar;
26(11):2753-64.
PMID: 25788530
The myeloid differentiation protein 88 (MyD88) adapter protein is an important mediator of kidney allograft rejection, yet the precise role of MyD88 signaling in directing the host immune response toward...
2.
Eby J, Kang H, Tully S, Bindeman W, Peiffer D, Chatterjee S, et al.
J Invest Dermatol
. 2015 Jan;
135(6):1574-1580.
PMID: 25634358
In vitiligo, gradual cutaneous depigmentation and cytotoxic T-cell activity against melanocytes are accompanied by a paucity of regulatory T cells (Tregs) in vitiligo patient skin, indicating that autoimmune responses are...
3.
Eby J, Kang H, Klarquist J, Chatterjee S, Mosenson J, Nishimura M, et al.
Pigment Cell Melanoma Res
. 2014 Jun;
27(6):1075-85.
PMID: 24935676
To generate a mouse model of spontaneous epidermal depigmentation, parental h3TA2 mice, expressing both a human-derived, tyrosinase-reactive T-cell receptor on T cells and the matching HLA-A2 transgene, were crossed to...
4.
Bryant J, Lerret N, Wang J, Kang H, Tasch J, Zhang Z, et al.
J Immunol
. 2014 May;
192(12):6092-101.
PMID: 24808363
We have previously shown that preemptive infusion of apoptotic donor splenocytes treated with the chemical cross-linker ethylcarbodiimide (ECDI-SPs) induces long-term allograft survival in full MHC-mismatched models of allogeneic islet and...
5.
Chatterjee S, Eby J, Al-Khami A, Soloshchenko M, Kang H, Kaur N, et al.
J Invest Dermatol
. 2013 Dec;
134(5):1285-1294.
PMID: 24366614
T-cell cytolytic activity targeting epidermal melanocytes is shown to cause progressive depigmentation and autoimmune vitiligo. By using the recently developed transgenic mice h3TA2 that carry T cells with a HLA-A2-restricted...
6.
Kang H, Chiang M, Ecklund D, Zhang L, Ramsey-Goldman R, Datta S
J Immunol
. 2012 May;
188(12):5970-80.
PMID: 22561152
In search of autoantigen-presenting cells that prime the pathogenic autoantibody-inducing Th cells of lupus, we found that CD41(+)CD151(+) cells among Lineage(-) (Lin(-)) CD117(+) (c-Kit(+)) CX3CR1(-) splenocytes depleted of known APCs...
7.
Kang H, Chiang M, Liu M, Ecklund D, Datta S
J Clin Immunol
. 2011 Feb;
31(3):379-94.
PMID: 21287397
Tolerance therapy with nucleosomal histone peptides H4(71-94), H4(16-39), or H1'(22-42) controls disease in lupus-prone SNF1 mice. It would be clinically important to determine whether a cocktail of the above epitopes...
8.
Kang H, Ecklund D, Liu M, Datta S
Arthritis Res Ther
. 2009 May;
11(2):R59.
PMID: 19405952
Introduction: Lupus patients need alternatives to steroids and cytotoxic drugs. We recently found that apigenin, a non-mutagenic dietary flavonoid, can sensitize recurrently activated, normal human T cells to apoptosis by...
9.
Kang H, Liu M, Datta S
J Immunol
. 2007 Jun;
178(12):7849-58.
PMID: 17548623
Subnanomolar doses of an unaltered, naturally occurring nucleosomal histone peptide epitope, H4(71-94), when injected s.c. into lupus-prone mice, markedly prolong lifespan by generating CD4+25+ and CD8+ regulatory T cells (Treg)...
10.
Kang H, Datta S
Int Rev Immunol
. 2006 Mar;
25(1-2):5-25.
PMID: 16531276
Naturally occurring, CD4+ CD25+ regulatory T cells that are exported from the thymus early in life play an important role in controlling organ-specific autoimmune diseases, but they may not be...