Hedy S Rennert
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Explore the profile of Hedy S Rennert including associated specialties, affiliations and a list of published articles.
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80
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4123
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Recent Articles
1.
Tsai Y, Nair K, Barot S, Xiang S, Kamath S, Melas M, et al.
J Natl Cancer Inst
. 2024 Jun;
116(10):1645-1653.
PMID: 38902947
The incidence of colorectal cancer (CRC) among individuals younger than age 50 (early-onset CRC [EOCRC]) has substantially increased, and yet the etiology and molecular mechanisms underlying this alarming rise remain...
2.
Schmit S, Tsai Y, Bonner J, Sanz-Pamplona R, Joshi A, Ugai T, et al.
BMC Genomics
. 2024 Apr;
25(1):409.
PMID: 38664626
Objective: To evaluate the contribution of germline genetics to regulating the briskness and diversity of T cell responses in CRC, we conducted a genome-wide association study to examine the associations...
3.
Tsai Y, Qu C, Bonner J, Sanz-Pamplona R, Lindsey S, Melas M, et al.
Front Immunol
. 2023 Nov;
14:1268117.
PMID: 37942321
Objective: Reduced diversity at Human Leukocyte Antigen (HLA) loci may adversely affect the host's ability to recognize tumor neoantigens and subsequently increase disease burden. We hypothesized that increased heterozygosity at...
4.
Dixon-Suen S, Lewis S, Martin R, English D, Boyle T, Giles G, et al.
Br J Sports Med
. 2022 Nov;
56(20):1157-1170.
PMID: 36328784
Objectives: Physical inactivity and sedentary behaviour are associated with higher breast cancer risk in observational studies, but ascribing causality is difficult. Mendelian randomisation (MR) assesses causality by simulating randomised trial...
5.
Fischer A, Rennert H, Rennert G
Int J Epidemiol
. 2022 Feb;
51(3):807-816.
PMID: 35134960
Background: Approximately one in six women in the USA takes antidepressants and a third use selective serotonin reuptake inhibitors (SSRIs) after breast cancer diagnosis. Recent investigation demonstrated serotonin receptor (5-HTR2B)...
6.
Escala-Garcia M, Canisius S, Keeman R, Beesley J, Anton-Culver H, Arndt V, et al.
Sci Rep
. 2021 Oct;
11(1):19787.
PMID: 34611289
Breast cancer metastasis accounts for most of the deaths from breast cancer. Identification of germline variants associated with survival in aggressive types of breast cancer may inform understanding of breast...
7.
Morra A, Escala-Garcia M, Beesley J, Keeman R, Canisius S, Ahearn T, et al.
Breast Cancer Res
. 2021 Aug;
23(1):86.
PMID: 34407845
Background: Given the high heterogeneity among breast tumors, associations between common germline genetic variants and survival that may exist within specific subgroups could go undetected in an unstratified set of...
8.
Ruth K, Day F, Hussain J, Martinez-Marchal A, Aiken C, Azad A, et al.
Nature
. 2021 Aug;
596(7872):393-397.
PMID: 34349265
Reproductive longevity is essential for fertility and influences healthy ageing in women, but insights into its underlying biological mechanisms and treatments to preserve it are limited. Here we identify 290...
9.
Park H, Neumeyer S, Michailidou K, Bolla M, Wang Q, Dennis J, et al.
Br J Cancer
. 2021 Aug;
125(8):1135-1145.
PMID: 34341517
Background: Despite a modest association between tobacco smoking and breast cancer risk reported by recent epidemiological studies, it is still equivocal whether smoking is causally related to breast cancer risk....
10.
Coignard J, Lush M, Beesley J, OMara T, Dennis J, Tyrer J, et al.
Nat Commun
. 2021 May;
12(1):2986.
PMID: 33990587
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-23162-4.