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Heather D Eshleman

Explore the profile of Heather D Eshleman including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 242
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Recent Articles
1.
Burgdorf C, Riley W, Akbar F, Zuehlke A, Bibb K, Eshleman H, et al.
PLoS One . 2024 Feb; 19(2):e0284235. PMID: 38354126
Health services, economics, and outcomes research (referred to as health economics research hereinafter) is one of the interdisciplinary sciences that the National Institutes of Health (NIH) supports in order to...
2.
Wood T, Westervelt K, Yoon J, Eshleman H, Levy R, Burnes H, et al.
mBio . 2022 May; 13(3):e0127022. PMID: 35638611
The type III secretion system is required for virulence of many pathogenic bacteria. Bacterial effector proteins delivered into target host cells by this system modulate host signaling pathways and processes...
3.
Lu R, Herrera B, Eshleman H, Fu Y, Bloom A, Li Z, et al.
PLoS Pathog . 2015 Oct; 11(10):e1005200. PMID: 26473364
The intracellular bacterial pathogen Shigella infects and spreads through the human intestinal epithelium. Effector proteins delivered by Shigella into cells promote infection by modulating diverse host functions. We demonstrate that...
4.
Eshleman H, Morgan D
J Cell Sci . 2014 Sep; 127(Pt 22):4974-83. PMID: 25236599
Sister chromatid bi-orientation on the mitotic spindle is essential for proper chromosome segregation. Defects in bi-orientation are sensed and corrected to prevent chromosome mis-segregation and aneuploidy. This response depends on...
5.
Hessa T, Sharma A, Mariappan M, Eshleman H, Gutierrez E, Hegde R
Nature . 2011 Jul; 475(7356):394-7. PMID: 21743475
A substantial proportion of the genome encodes membrane proteins that are delivered to the endoplasmic reticulum by dedicated targeting pathways. Membrane proteins that fail targeting must be rapidly degraded to...
6.
Schwartz R, Lakdawala S, Eshleman H, Russell M, Carson C, Weitzman M
J Virol . 2008 Jul; 82(18):9043-55. PMID: 18614635
The E1b55K and E4orf6 proteins of adenovirus type 5 (Ad5) assemble into a complex together with cellular proteins including cullin 5, elongins B and C, and Rbx1. This complex possesses...