Haynes Heaton
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Explore the profile of Haynes Heaton including associated specialties, affiliations and a list of published articles.
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10
Citations
658
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Recent Articles
1.
Rahola N, Ayala D, Bouafou L, Makanga B, Johnson H, Heaton H, et al.
Wellcome Open Res
. 2025 Feb;
9:553.
PMID: 39931114
We present a genome assembly from an individual female (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae). The genome sequence is 224 megabases in span. Most of the assembly is scaffolded...
2.
Weerakoon M, Lee S, Mitchell E, Heaton H
BMC Bioinformatics
. 2025 Jan;
26(1):17.
PMID: 39815230
Background: Pacific Biosciences (PacBio) circular consensus sequencing (CCS), also known as high fidelity (HiFi) technology, has revolutionized modern genomics by producing long (10 + kb) and highly accurate reads. This...
3.
Makanga B, Ayala D, Rahola N, Bouafou L, Johnson H, Heaton H, et al.
Wellcome Open Res
. 2024 Nov;
9:554.
PMID: 39507815
We present a genome assembly from an individual female (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae) from Lopé, Gabon. The genome sequence is 225.7 megabases in span. Most of the...
4.
Bouafou L, Ayala D, Makanga B, Rahola N, Johnson H, Heaton H, et al.
Wellcome Open Res
. 2024 Oct;
9:551.
PMID: 39429628
We present genome assembly from individual female (African malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae) from Lopé, Gabon. The genome sequence is 270 megabases in span. Most of the assembly is...
5.
Nsango S, Agbor J, Ayala D, Johnson H, Heaton H, Wagah M, et al.
Wellcome Open Res
. 2023 Dec;
8:507.
PMID: 38046191
We present a genome assembly from an individual male (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae), from a wild population in Cameroon. The genome sequence is 271 megabases in span....
6.
Habtewold T, Wagah M, Tambwe M, Moore S, Windbichler N, Christophides G, et al.
Wellcome Open Res
. 2023 Jul;
8:74.
PMID: 37424773
We present a genome assembly from an individual female (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae), Ifakara strain. The genome sequence is 264 megabases in span. Most of the assembly...
7.
Ayala D, Akone-Ella O, Kengne P, Johnson H, Heaton H, Collins J, et al.
Wellcome Open Res
. 2023 Mar;
7():287.
PMID: 36874567
We present a genome assembly from an individual female (the malaria mosquito; Arthropoda; Insecta; Diptera; Culicidae). The genome sequence is 251 megabases in span. The majority of the assembly is...
8.
Heaton H, Talman A, Knights A, Imaz M, Gaffney D, Durbin R, et al.
Nat Methods
. 2020 May;
17(6):615-620.
PMID: 32366989
Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for samples containing a mixture of genotypes, whether they are natural or experimentally combined. Multiplexing across donors is a popular experimental...
9.
Howick V, Russell A, Andrews T, Heaton H, Reid A, Natarajan K, et al.
Science
. 2019 Aug;
365(6455).
PMID: 31439762
Malaria parasites adopt a remarkable variety of morphological life stages as they transition through multiple mammalian host and mosquito vector environments. We profiled the single-cell transcriptomes of thousands of individual...
10.
Zook J, McDaniel J, Olson N, Wagner J, Parikh H, Heaton H, et al.
Nat Biotechnol
. 2019 Apr;
37(5):561-566.
PMID: 30936564
Benchmark small variant calls are required for developing, optimizing and assessing the performance of sequencing and bioinformatics methods. Here, as part of the Genome in a Bottle (GIAB) Consortium, we...