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Hayley Gooding

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Citations 25
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Recent Articles
1.
Agrez M, Chandler C, Thurecht K, Fletcher N, Liu F, Subramaniam G, et al.
Sci Rep . 2024 Nov; 14(1):26737. PMID: 39501043
The identification of adjuvants to improve vaccination efficacy is a major unmet need. One approach is to augment the functionality of dendritic cells (DCs) by using Toll-like receptor-9 (TLR9) agonists...
2.
Agrez M, Chandler C, Thurecht K, Fletcher N, Liu F, Subramaniam G, et al.
Sci Rep . 2023 Nov; 13(1):19741. PMID: 37957274
Cancers and autoimmune diseases commonly co-exist and immune checkpoint inhibitor therapy (ICI) exacerbates autoimmune pathologies. We recently described a lipidic peptide, designated IK14004, that promotes expansion of immunosuppressive T regulatory...
3.
Agrez M, Rybchyn M, De Silva W, Mason R, Chandler C, Piva T, et al.
Sci Rep . 2023 Jul; 13(1):11702. PMID: 37474630
Ultraviolet radiation (UVR) induces immunosuppression and DNA damage, both of which contribute to the rising global incidence of skin cancer including melanoma. Nucleotide excision repair, which is activated upon UVR-induced...
4.
Agrez M, Rzepecka J, Turner D, Knox G, Chandler C, Howard C, et al.
Sci Rep . 2022 Jul; 12(1):11185. PMID: 35778468
T cell-dendritic cell (DC) interactions contribute to reciprocal stimulation leading to DC maturation that results in production of interleukin-12 (IL-12) and interferon-gamma (IFN-γ). Both cytokines have been implicated in autoimmune...
5.
Vinuela-Fernandez I, Sun L, Jerina H, Curtis J, Allchorne A, Gooding H, et al.
Neuropharmacology . 2013 Nov; 79:136-51. PMID: 24269608
Effective relief from chronic hypersensitive pain states remains an unmet need. Here we report the discovery that the TRPM8 ion channel, co-operating with the 5-HT(1B) receptor (5-HT(1B)R) in a subset...