Hayden N Brochu
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Explore the profile of Hayden N Brochu including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
25
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Recent Articles
1.
Characterization of vaginal microbiomes in clinician-collected bacterial vaginosis diagnosed samples
Brochu H, Zhang Q, Song K, Wang L, Deare E, Williams J, et al.
Microbiol Spectr
. 2025 Feb;
:e0258224.
PMID: 39998243
Bacterial vaginosis (BV) is a type of vaginal inflammation caused by bacterial overgrowth, upsetting the healthy microbiome of the vagina. Existing clinical testing for BV is primarily based upon physical...
2.
Brochu H, Smith E, Jeong S, Carlson M, Hansen S, Tisoncik-Go J, et al.
Microbiol Spectr
. 2024 Sep;
12(11):e0128524.
PMID: 39345211
Rhesus cytomegalovirus expressing simian immunodeficiency virus (RhCMV/SIV) vaccines protect ~59% of vaccinated rhesus macaques against repeated limiting-dose intra-rectal exposure with highly pathogenic SIVmac239M, but the exact mechanism responsible for the...
3.
Brochu H, Song K, Zhang Q, Zeng Q, Shafi A, Robinson M, et al.
Sci Rep
. 2024 Aug;
14(1):20249.
PMID: 39215120
The COVID-19 pandemic brought forth an urgent need for widespread genomic surveillance for rapid detection and monitoring of emerging SARS-CoV-2 variants. It necessitated design, development, and deployment of a nationwide...
4.
Brochu H, Smith E, Jeong S, Carlson M, Hansen S, Tisoncik-Go J, et al.
bioRxiv
. 2024 Mar;
PMID: 38464179
Background: RhCMV/SIV vaccines protect ∼59% of vaccinated rhesus macaques against repeated limiting-dose intra-rectal exposure with highly pathogenic SIVmac239M, but the exact mechanism responsible for the vaccine efficacy is not known....
5.
Song K, Brochu H, Zhang Q, Williams J, Iyer L
Viruses
. 2023 Dec;
15(12).
PMID: 38140568
The 2022 global Mpox outbreak swiftly introduced unforeseen diversity in the monkeypox virus (MPXV) population, resulting in numerous Clade IIb sublineages. This propagation of new MPXV mutations warrants the thorough...
6.
Walsh E, Tollison T, Brochu H, Shaw B, Diveley K, Chou H, et al.
J Immunol
. 2022 Jan;
208(3):762-771.
PMID: 34987112
Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired H and L chains of Igs and VDJ and VJ chains of TCRs from thousands of single...
7.
Brochu H, Tseng E, Smith E, Thomas M, Jones A, Diveley K, et al.
J Immunol
. 2020 May;
204(12):3434-3444.
PMID: 32376650
The diversity of Ig and TCR repertoires is a focal point of immunological studies. Rhesus macaques () are key for modeling human immune responses, placing critical importance on the accurate...
8.
Lemler D, Brochu H, Yang F, Harrell E, Peng X
Vaccines (Basel)
. 2017 Oct;
5(4).
PMID: 29053596
Research over the past decade has clearly shown that long non-coding RNAs (lncRNAs) are functional. Many lncRNAs can be related to immunity and the host response to viral infection, but...