Hayato Fukusumi
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Explore the profile of Hayato Fukusumi including associated specialties, affiliations and a list of published articles.
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15
Citations
91
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Recent Articles
1.
Kanemura Y, Yamamoto A, Katsuma A, Fukusumi H, Shofuda T, Kanematsu D, et al.
Cells
. 2024 Apr;
13(8.
PMID: 38667286
Ischemic stroke is a major cerebrovascular disease with high morbidity and mortality rates; however, effective treatments for ischemic stroke-related neurological dysfunction have yet to be developed. In this study, we...
2.
Fukusumi H, Togo K, Beck G, Shofuda T, Kanematsu D, Yamamoto A, et al.
Stem Cell Res
. 2023 May;
69:103122.
PMID: 37209469
Infantile neuroaxonal dystrophy (INAD) is a rare neurodegenerative disease caused mainly by homozygous or compound heterozygous mutations in the PLA2G6 gene. We generated a human induced pluripotent stem cell (hiPSC)...
3.
Okada M, Kawagoe Y, Takasugi T, Nozumi M, Ito Y, Fukusumi H, et al.
Neurochem Res
. 2022 May;
47(9):2683.
PMID: 35608791
No abstract available.
4.
Okada M, Kawagoe Y, Takasugi T, Nozumi M, Ito Y, Fukusumi H, et al.
Neurochem Res
. 2022 Mar;
47(9):2668-2682.
PMID: 35347634
Mammalian axon growth has mechanistic similarities with axon regeneration. The growth cone is an important structure that is involved in both processes, and GAP-43 (growth associated protein-43 kDa) is believed...
5.
Togo K, Fukusumi H, Shofuda T, Ohnishi H, Yamazaki H, Hayashi M, et al.
Mol Brain
. 2021 Oct;
14(1):149.
PMID: 34629097
The generation of mature synaptic structures using neurons differentiated from human-induced pluripotent stem cells (hiPSC-neurons) is expected to be applied to physiological studies of synapses in human cells and to...
6.
Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, et al.
FEBS Open Bio
. 2020 Dec;
11(2):354-366.
PMID: 33301617
Parkinson's disease (PD) is a neurodegenerative disorder caused by the selective loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Lewy bodies (LBs), another histological hallmark of...
7.
Fukusumi H, Handa Y, Shofuda T, Kanemura Y
J Pharmacol Sci
. 2019 Sep;
140(4):331-336.
PMID: 31501056
Various chemicals, including pharmaceuticals, can induce acute or delayed neurotoxicity in humans. Because isolation of human primary neurons is extremely difficult, toxicity tests for these agents have been performed using...
8.
Fukusumi H, Handa Y, Shofuda T, Kanemura Y
PeerJ
. 2018 Jan;
6:e4187.
PMID: 29312819
Since the development of human-induced pluripotent stem cells (hiPSCs), various types of hiPSC-derived cells have been established for regenerative medicine and drug development. Neural stem/progenitor cells (NSPCs) derived from hiPSCs...
9.
Kanemura Y, Sumida M, Okita Y, Yoshioka E, Yamamoto A, Kanematsu D, et al.
Anticancer Res
. 2017 Jul;
37(7):3921-3932.
PMID: 28668896
In this clinical study, we investigated the safety and clinical usefulness of systemic adoptive immunotherapy using autologous lymphokine-activated αβ T-cells (αβ T-cells), combined with standard therapies, in patients with malignant...
10.
Sugai K, Fukuzawa R, Shofuda T, Fukusumi H, Kawabata S, Nishiyama Y, et al.
Mol Brain
. 2016 Sep;
9(1):85.
PMID: 27642008
The risk of tumorigenicity is a hurdle for regenerative medicine using induced pluripotent stem cells (iPSCs). Although teratoma formation is readily distinguishable, the malignant transformation of iPSC derivatives has not...