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Hatsune Chiba

Explore the profile of Hatsune Chiba including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1704
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Recent Articles
1.
Ohishi H, Au Yeung W, Unoki M, Ichiyanagi K, Fukuda K, Maenohara S, et al.
Genes Cells . 2019 Nov; 25(1):54-64. PMID: 31733167
Monoallelic gene expression occurs in various mammalian cells and can be regulated genetically, epigenetically and/or stochastically. We identified 145 monoallelically expressed genes (MoEGs), including seven known imprinted genes, in mouse...
2.
Dodo M, Kitamura H, Shima H, Saigusa D, Wati S, Ota N, et al.
J Biochem . 2018 Dec; 165(4):323-334. PMID: 30590713
Metabolites are sensitive indicators of moment-to-moment cellular status and activity. Expecting that tissue-specific metabolic signatures unveil a unique function of the tissue, we examined metabolomes of mouse liver and testis...
3.
Hiura H, Hattori H, Kobayashi N, Okae H, Chiba H, Miyauchi N, et al.
Clin Epigenetics . 2017 Aug; 9:79. PMID: 28785370
Background: Frozen-thawed embryo transfer (FET) is increasingly available for the improvement of the success rate of assisted reproductive technologies other than fresh embryo transfer (ET). There have been numerous findings...
4.
Kobayashi N, Okae H, Hiura H, Chiba H, Shirakata Y, Hara K, et al.
PLoS One . 2016 Nov; 11(11):e0167127. PMID: 27880848
DNA methylation plays important roles in the production and functioning of spermatozoa. Recent studies have suggested that DNA methylation patterns in spermatozoa can change with age, but the regions susceptible...
5.
Hamada H, Okae H, Toh H, Chiba H, Hiura H, Shirane K, et al.
Am J Hum Genet . 2016 Nov; 99(5):1045-1058. PMID: 27843122
DNA methylation is globally reprogrammed after fertilization, and as a result, the parental genomes have similar DNA-methylation profiles after implantation except at the germline differentially methylated regions (gDMRs). We and...
6.
Kitamura A, Miyauchi N, Hamada H, Hiura H, Chiba H, Okae H, et al.
Congenit Anom (Kyoto) . 2015 Jul; 55(3):133-44. PMID: 26212350
The most common form of male infertility is a low sperm count, known as oligozoospermia. Studies suggest that oligozoospermia is associated with epigenetic alterations. Epigenetic alterations in sperm, which may...
7.
Okae H, Chiba H, Hiura H, Hamada H, Sato A, Utsunomiya T, et al.
PLoS Genet . 2014 Dec; 10(12):e1004868. PMID: 25501653
DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced representation bisulfite sequencing (RRBS) studies suggest that the methylome dynamics are essentially conserved...
8.
Hiura H, Okae H, Chiba H, Miyauchi N, Sato F, Sato A, et al.
Reprod Med Biol . 2014 Oct; 13(4):193-202. PMID: 25298744
There has been an increase in incidence reports of rare imprinting disorders associated with assisted reproductive technology (ART). ART, including in vitro fertilization and intracytoplasmic sperm injections, is an important...
9.
Okae H, Matoba S, Nagashima T, Mizutani E, Inoue K, Ogonuki N, et al.
Hum Mol Genet . 2013 Oct; 23(4):992-1001. PMID: 24105465
Animals cloned by somatic cell nuclear transfer (SCNT) provide a unique model for understanding the mechanisms of nuclear epigenetic reprogramming to a state of totipotency. Though many phenotypic abnormalities have...
10.
Chiba H, Hiura H, Okae H, Miyauchi N, Sato F, Sato A, et al.
Pediatr Int . 2013 Aug; 55(5):542-9. PMID: 23919517
There have been increased incident reports of rare imprinting disorders associated with assisted reproductive technology (ART). ART is an important treatment for infertile people of reproductive age and is increasingly...