Hashini M Batugedara
Overview
Explore the profile of Hashini M Batugedara including associated specialties, affiliations and a list of published articles.
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5
Citations
157
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Recent Articles
1.
Van Hulst G, Batugedara H, Jorssen J, Louis R, Bureau F, Desmet C
Biochem Pharmacol
. 2020 Apr;
179:113963.
PMID: 32278006
Eosinophils are a type of granulated innate immune cells that have long been implicated in a specific type of asthma, referred to as eosinophilic asthma. Several immunotherapeutics that target and...
2.
Batugedara H, Argueta D, Jang J, Lu D, Macchietto M, Kaur J, et al.
Infect Immun
. 2018 Aug;
86(11).
PMID: 30104215
Helminths have coevolved with their hosts, resulting in the development of specialized host immune mechanisms and parasite-specific regulatory products. Identification of new pathways that regulate helminth infection could provide a...
3.
Batugedara H, Li J, Chen G, Lu D, Patel J, Jang J, et al.
J Leukoc Biol
. 2018 Jul;
104(4):855-869.
PMID: 29992625
Resistin-like molecule α (RELMα) is a highly secreted protein in type 2 (Th2) cytokine-induced inflammation including helminth infection and allergy. In infection with Nippostrongylus brasiliensis (Nb), RELMα dampens Th2 inflammatory...
4.
Pine G, Batugedara H, Nair M
Cytokine
. 2018 Jun;
110:442-451.
PMID: 29866514
The Resistin-Like Molecules (RELM) α, β, and γ and their namesake, resistin, share structural and sequence homology but exhibit significant diversity in expression and function within their mammalian host. RELM...
5.
Jang J, Li J, Gambini L, Batugedara H, Sati S, Lazar M, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(48):E10399-E10408.
PMID: 29133417
Helminths trigger multiple immunomodulatory pathways that can protect from sepsis. Human resistin (hRetn) is an immune cell-derived protein that is highly elevated in helminth infection and sepsis. However, the function...