Haseeb Mughal
Overview
Explore the profile of Haseeb Mughal including associated specialties, affiliations and a list of published articles.
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5
Citations
48
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Recent Articles
1.
Li B, Jiang A, Raji I, Atyeo C, Raimondo T, Gordon A, et al.
Nat Biomed Eng
. 2025 Jan;
9(2):280.
PMID: 39820560
No abstract available.
2.
Witten J, Raji I, Manan R, Beyer E, Bartlett S, Tang Y, et al.
Nat Biotechnol
. 2024 Dec;
PMID: 39658727
Ionizable lipids are a key component of lipid nanoparticles, the leading nonviral messenger RNA delivery technology. Here, to advance the identification of ionizable lipids beyond current methods, which rely on...
3.
Li B, Jiang A, Raji I, Atyeo C, Raimondo T, Gordon A, et al.
Nat Biomed Eng
. 2023 Sep;
9(2):167-184.
PMID: 37679571
To elicit optimal immune responses, messenger RNA vaccines require intracellular delivery of the mRNA and the careful use of adjuvants. Here we report a multiply adjuvanted mRNA vaccine consisting of...
4.
Mughal H, Bell E, Mughal K, Derbyshire E, Freundlich J
ACS Infect Dis
. 2022 Jul;
8(8):1553-1562.
PMID: 35894649
The need for novel antimalarials is apparent given the continuing disease burden worldwide, despite significant drug discovery advances from the bench to the bedside. In particular, small-molecule agents with potent...
5.
Mughal H, Szostak M
Org Biomol Chem
. 2021 Apr;
19(15):3274-3286.
PMID: 33899862
Azetidines represent one of the most important four-membered heterocycles used in organic synthesis and medicinal chemistry. The reactivity of azetidines is driven by a considerable ring strain, while at the...
6.
Mughal H, Wang H, Zimmerman M, Paradis M, Freundlich J
ACS Pharmacol Transl Sci
. 2021 Feb;
4(1):338-343.
PMID: 33615183
An early hurdle in the optimization of small-molecule chemical probes and drug discovery entities is the attainment of sufficient exposure in the mouse via oral administration of the compound. While...