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Harshal Waghulde

Explore the profile of Harshal Waghulde including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 359
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Recent Articles
1.
Ashraf U, Atari E, Alasmari F, Waghulde H, Kumar V, Sari Y, et al.
Biomedicines . 2023 Jan; 11(1). PMID: 36672619
The genetic and molecular basis of developing high blood pressure and renal disease are not well known. Dahl salt-sensitive (SS-) rats fed a 2% NaCl diet for six weeks have...
2.
Waghulde H, Galla S, Chakraborty S, Joe B
Hypertension . 2019 Jan; 73(2):e11. PMID: 30595121
No abstract available.
3.
Waghulde H, Cheng X, Galla S, Mell B, Cai J, Pruett-Miller S, et al.
Hypertension . 2018 Oct; 72(5):1125-1132. PMID: 30354811
G-protein-coupled estrogen receptor, Gper1, has been implicated in cardiovascular disease, but its mechanistic role in blood pressure control is poorly understood. Here, we demonstrate that genetically salt-sensitive hypertensive rats with...
4.
Waghulde H, Pillai R, Cheng X, Nie Y, Mell B, Joe B
J Hypertens . 2018 Apr; 36(7):1486-1491. PMID: 29634662
Background: Previously, using linkage analysis and substitution mapping, two closely-linked interactive blood pressure quantitative trait loci (QTLs), BP QTL1 and BP QTL2, were located within a 13.96 Mb region from...
5.
Kumarasamy S, Waghulde H, Cheng X, Haller S, Mell B, Abhijith B, et al.
Physiol Genomics . 2018 Mar; 50(5):369-375. PMID: 29570433
Hypertension is a classic example of a complex polygenic trait, impacted by quantitative trait loci (QTL) containing candidate genes thought to be responsible for blood pressure (BP) control in mammals....
6.
Cheng X, Waghulde H, Mell B, Morgan E, Pruett-Miller S, Joe B
PLoS Genet . 2017 Aug; 13(8):e1006961. PMID: 28827789
Multiple GWAS studies have reported strong association of cardiac QT-interval to a region on HSA17. Interestingly, a rat locus homologous to this region is also linked to QT-intervals. The high...
7.
Haller S, Kumarasamy S, Folt D, Wuescher L, Stepkowski S, Karamchandani M, et al.
Kidney Int . 2016 Oct; 91(2):365-374. PMID: 27692815
High blood pressure is a common cause of chronic kidney disease. Because CD40, a member of the tumor necrosis factor receptor family, has been linked to the progression of kidney...
8.
Nie Y, Kumarasamy S, Waghulde H, Cheng X, Mell B, Czernik P, et al.
Physiol Genomics . 2016 Apr; 48(6):409-19. PMID: 27113531
Through linkage analysis of the Dahl salt-sensitive (S) rat and the spontaneously hypertensive rat (SHR), a blood pressure (BP) quantitative trait locus (QTL) was previously located on rat chromosome 9....
9.
Cheng X, Waghulde H, Mell B, Smedlund K, Vazquez G, Joe B
PLoS One . 2016 Apr; 11(4):e0153519. PMID: 27073989
This study is focused on a translationally significant, genome-wide-association-study (GWAS) locus for cardiovascular disease (QT-interval) on human chromosome 17. We have previously validated and high resolution mapped the homologous genomic...
10.
Mell B, Jala V, Mathew A, Byun J, Waghulde H, Zhang Y, et al.
Physiol Genomics . 2015 Apr; 47(6):187-97. PMID: 25829393
The gut microbiota plays a critical role in maintaining physiological homeostasis. This study was designed to evaluate whether gut microbial composition affects hypertension. 16S rRNA genes obtained from cecal samples...