Harsh Bahrar
Overview
Explore the profile of Harsh Bahrar including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
179
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0
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Recent Articles
1.
van Tuijl J, van Heck J, Bahrar H, Broeders W, Wijma J, Ten Have Y, et al.
iScience
. 2024 Nov;
27(11):111103.
PMID: 39493874
Brief exposure of monocytes to atherogenic molecules, such as oxidized lipoproteins, triggers a persistent pro-inflammatory phenotype, named trained immunity. In mice, transient high-fat diet leads to trained immunity, which aggravates...
2.
Tercan H, van Broekhoven A, Bahrar H, Opstal T, Cossins B, Rother N, et al.
Clin Pharmacol Ther
. 2024 Aug;
116(5):1325-1333.
PMID: 39115262
Recent landmark trials showed that colchicine provides a substantial benefit in reducing major cardiovascular events in patients with coronary artery disease. Yet, its exact mechanism of action is still poorly...
3.
Warmbrunn M, Bahrar H, de Clercq N, Koopen A, de Groot P, Rutten J, et al.
Nutrients
. 2024 Jun;
16(12).
PMID: 38931177
Context/objective: In order to better understand which metabolic differences are related to insulin resistance in metabolic syndrome (MetSyn), we used hyperinsulinemic-euglycemic (HE) clamps in individuals with MetSyn and related peripheral...
4.
Roring R, Debisarun P, Botey-Bataller J, Suen T, Bulut O, Kilic G, et al.
J Clin Invest
. 2024 Jan;
134(7).
PMID: 38290093
The measles, mumps, and rubella (MMR) vaccine protects against all-cause mortality in children, but the immunological mechanisms mediating these effects are poorly known. We systematically investigated whether MMR can induce...
5.
van den Munckhof I, Bahrar H, Schraa K, Brand T, Ter Horst R, van der Graaf M, et al.
Int J Obes (Lond)
. 2023 Dec;
48(4):523-532.
PMID: 38135702
Background And Aims: Obesity predisposes to metabolic and cardiovascular diseases. Adipose tissue inflammation and systemic inflammation contribute to these complications. There are strong sex differences in adipose tissue distribution and...
6.
Bahrar H, Bekkering S, Stienstra R, Netea M, Riksen N
Cardiovasc Res
. 2023 Feb;
119(18):2774-2786.
PMID: 36795085
Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be crucial for these effects. Obesity and associated...
7.
Dominguez-Andres J, Arts R, Bekkering S, Bahrar H, Blok B, de Bree L, et al.
STAR Protoc
. 2021 Mar;
2(1):100365.
PMID: 33718890
A growing number of studies show that innate immune cells can undergo functional reprogramming, facilitating a faster and enhanced response to heterologous secondary stimuli. This concept has been termed "trained...
8.
Brand T, Iida M, Stein A, Corrigan K, Braverman C, Coan J, et al.
Clin Cancer Res
. 2018 Dec;
24(23):6099.
PMID: 30510088
No abstract available.
9.
Iida M, Bahrar H, Brand T, Pearson H, Coan J, Orbuch R, et al.
Mol Cancer Ther
. 2016 Jul;
15(9):2175-86.
PMID: 27422810
Cetuximab, an antibody against the EGFR, has shown efficacy in treating head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer, and non-small cell lung cancer (NSCLC). Despite the clinical...
10.
Brand T, Iida M, Stein A, Corrigan K, Braverman C, Coan J, et al.
Clin Cancer Res
. 2015 Mar;
21(11):2601-12.
PMID: 25767293
Purpose: Head and neck squamous cell carcinoma (HNSCC) represents the eighth most common malignancy worldwide. Standard-of-care treatments for patients with HNSCC include surgery, radiation, and chemotherapy. In addition, the anti-EGFR...