Harold P Swerdlow
Overview
Explore the profile of Harold P Swerdlow including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
3324
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0
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Recent Articles
1.
Stephenson W, Donlin L, Butler A, Rozo C, Bracken B, Rashidfarrokhi A, et al.
Nat Commun
. 2018 Feb;
9(1):791.
PMID: 29476078
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively parallel cellular profiling. While this approach offers the exciting promise to deconvolute cellular heterogeneity in diseased tissues, the lack...
2.
Macaulay I, Haerty W, Kumar P, Li Y, Hu T, Teng M, et al.
Nat Methods
. 2015 Apr;
12(6):519-22.
PMID: 25915121
The simultaneous sequencing of a single cell's genome and transcriptome offers a powerful means to dissect genetic variation and its effect on gene expression. Here we describe G&T-seq, a method...
3.
Quail M, Smith M, Jackson D, Leonard S, Skelly T, Swerdlow H, et al.
BMC Genomics
. 2014 Feb;
15:110.
PMID: 24507442
Background: A minor but significant fraction of samples subjected to next-generation sequencing methods are either mixed-up or cross-contaminated. These events can lead to false or inconclusive results. We have therefore...
4.
Oyola S, Gu Y, Manske M, Otto T, OBrien J, Alcock D, et al.
J Clin Microbiol
. 2012 Dec;
51(3):745-51.
PMID: 23224084
The cost of whole-genome sequencing (WGS) is decreasing rapidly as next-generation sequencing technology continues to advance, and the prospect of making WGS available for public health applications is becoming a...
5.
Quail M, Smith M, Coupland P, Otto T, Harris S, Connor T, et al.
BMC Genomics
. 2012 Jul;
13:341.
PMID: 22827831
Background: Next generation sequencing (NGS) technology has revolutionized genomic and genetic research. The pace of change in this area is rapid with three major new sequencing platforms having been released...
6.
Oyola S, Otto T, Gu Y, Maslen G, Manske M, Campino S, et al.
BMC Genomics
. 2012 Jan;
13:1.
PMID: 22214261
Background: Massively parallel sequencing technology is revolutionizing approaches to genomic and genetic research. Since its advent, the scale and efficiency of Next-Generation Sequencing (NGS) has rapidly improved. In spite of...
7.
Quail M, Otto T, Gu Y, Harris S, Skelly T, McQuillan J, et al.
Nat Methods
. 2011 Dec;
9(1):10-1.
PMID: 22205512
No abstract available.
8.
Bentley D, Balasubramanian S, Swerdlow H, Smith G, Milton J, Brown C, et al.
Nature
. 2008 Nov;
456(7218):53-9.
PMID: 18987734
DNA sequence information underpins genetic research, enabling discoveries of important biological or medical benefit. Sequencing projects have traditionally used long (400-800 base pair) reads, but the existence of reference sequences...