Haoqing Wang
Overview
Explore the profile of Haoqing Wang including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
857
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Recent Articles
1.
Yin C, Imms P, Chowdhury N, Chaudhari N, Ping H, Wang H, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(10):e2413442122.
PMID: 39993207
Brain age (BA), distinct from chronological age (CA), can be estimated from MRIs to evaluate neuroanatomic aging in cognitively normal (CN) individuals. BA, however, is a cross-sectional measure that summarizes...
2.
Xu J, Chen G, Wang H, Cao S, Heng J, Deupi X, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(48):e2414544121.
PMID: 39565314
Advances in singe-particle cryo-electron microscopy (cryo-EM) have made it possible to solve the structures of numerous Family A and Family B G protein-coupled receptors (GPCRs) in complex with G proteins...
3.
Ople R, Ramos-Gonzalez N, Li Q, Sobecks B, Aydin D, Powers A, et al.
ACS Cent Sci
. 2024 Sep;
10(8):1490-1503.
PMID: 39220695
The mu opioid receptor (μOR) is a target for clinically used analgesics. However, adverse effects, such as respiratory depression and physical dependence, necessitate the development of alternative treatments. Recently we...
4.
Imms P, Chaudhari N, Chowdhury N, Wang H, Yu X, Amgalan A, et al.
Geroscience
. 2024 Aug;
47(1):915-934.
PMID: 39153054
Identifying cognitively normal (CN) older adults who will convert to cognitive impairment (CI) due to Alzheimer's disease is crucial for early intervention. Clinical and neuroimaging measures were acquired from 301...
5.
OBrien E, Rangari V, El Daibani A, Eans S, Hammond H, White E, et al.
Nature
. 2024 Jul;
631(8021):686-693.
PMID: 38961287
The µ-opioid receptor (µOR) is a well-established target for analgesia, yet conventional opioid receptor agonists cause serious adverse effects, notably addiction and respiratory depression. These factors have contributed to the...
6.
Kumar K, Wang H, Habrian C, Latorraca N, Xu J, OBrien E, et al.
Nature
. 2024 May;
629(8013):E13.
PMID: 38702522
No abstract available.
7.
Kumar K, Wang H, Habrian C, Latorraca N, Xu J, OBrien E, et al.
Nature
. 2024 Apr;
629(8013):951-956.
PMID: 38632403
Metabotropic glutamate receptors belong to a family of G protein-coupled receptors that are obligate dimers and possess a large extracellular ligand-binding domain that is linked via a cysteine-rich domain to...
8.
Casiraghi M, Wang H, Brennan P, Habrian C, Hubner H, Schmidt M, et al.
bioRxiv
. 2024 Apr;
PMID: 38586060
G protein coupled receptors (GPCRs) exhibit varying degrees of selectivity for different G protein isoforms. Despite the abundant structures of GPCR-G protein complexes, little is known about the mechanism of...
9.
Kumar K, Wang H, Habrian C, Latorraca N, Xu J, OBrien E, et al.
bioRxiv
. 2023 Sep;
PMID: 37693614
Metabotropic glutamate receptors belong to a family of G protein-coupled receptors that are obligate dimers and possess a large extracellular ligand-binding domain (ECD) that is linked via a cysteine-rich domain...
10.
Solomon P, Bracken C, Carozza J, Wang H, Young E, Wellner A, et al.
Nat Chem Biol
. 2023 Jul;
20(1):30-41.
PMID: 37400538
Ectodomain phosphatase/phosphodiesterase-1 (ENPP1) is overexpressed on cancer cells and functions as an innate immune checkpoint by hydrolyzing extracellular cyclic guanosine monophosphate adenosine monophosphate (cGAMP). Biologic inhibitors have not yet been...