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Hans-Ullrich Spiegel

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Recent Articles
1.
Juratli M, Becker F, Palmes D, Stoppeler S, Bahde R, Kebschull L, et al.
BMC Med Educ . 2021 May; 21(1):295. PMID: 34024279
Background: Microsurgical techniques are an important part of clinical and experimental research. Here we present our step-by-step microsurgery training course developed at the Münster University Hospital. The goal of this...
2.
Kebschull L, Theilmann L, Mohr A, Uennigmann W, Stoeppeler S, Heitplatz B, et al.
Biosci Rep . 2017 Nov; 37(6). PMID: 29127105
Ischemia-reperfusion injury (IRI) remains a key component of graft damage during transplantation. Erythropoietin (EPO) induces anti-inflammatory and anti-apoptotic effects via the EPOR/βcR complex, with a potential risk of thrombosis. Previous...
3.
Rijcken E, Sachs L, Fuchs T, Spiegel H, Neumann P
J Surg Res . 2013 Dec; 187(1):202-10. PMID: 24290527
Background: Failure of anastomotic healing in the gastrointestinal tract is a major source of surgery-related morbidity, repeated surgical procedures, and impaired quality of life. Growth factors have been shown to...
4.
Bahde R, Kapoor S, Viswanathan P, Spiegel H, Gupta S
Hepatology . 2013 Oct; 59(3):1107-17. PMID: 24114775
Unlabelled: Cell transplantation-induced hepatic ischemia and recruitment of vasoconstrictors (e.g., endothelin-1; Edn1) leads to clearance of transplanted cells and poses problems for liver repopulation. Therefore, we determined whether darusentan (DAR),...
5.
Persigehl T, Ring J, Budny T, Hahnenkamp A, Stoeppeler S, Schwartz L, et al.
Mol Imaging . 2013 Aug; 12(7):1-11. PMID: 23962676
The aim of this study was to evaluate a robust magnetic resonance (MR) vessel size imaging (VSI) method for the noninvasive assessment of mean vessel size in solid tumors in...
6.
Siaj R, Sauer V, Stoppeler S, Gerss J, Spiegel H, Kohler G, et al.
Hepatol Int . 2012 Nov; 6(4):770-7. PMID: 23125884
Purpose: MicroRNA-122 (miR-122) has recently been shown to represent a novel biomarker of liver disease. However, the presence of serum miR-122 after liver injury was mostly studied at singular time...
7.
Siaj R, Sauer V, Stoppeler S, Spiegel H, Kohler G, Zibert A, et al.
World J Gastroenterol . 2012 Nov; 18(39):5542-50. PMID: 23112546
Aim: To investigate the impact of dietary copper given at different time points on the onset of fulminant hepatitis. Methods: The Long-Evans cinnamon (LEC) rat model of Wilson's disease (WD)...
8.
Sauer V, Siaj R, Stoppeler S, Bahde R, Spiegel H, Kohler G, et al.
Liver Transpl . 2011 Dec; 18(2):248-59. PMID: 22140056
The outcome of consecutive hepatocyte transplants was explored in a rat model of Wilson's disease before the onset of fulminant hepatitis without preconditioning regimens. Rats received a high-copper diet in...
9.
Rosenstengel S, Stoeppeler S, Bahde R, Spiegel H, Palmes D
J Invest Surg . 2011 Nov; 24(6):273-82. PMID: 22047200
This study investigates the impact of rat strain on the development of nonalcoholic fatty liver disease (NAFLD) focusing on morphological features and microcirculation. Male rats of Lewis, Wistar, and Sprague...
10.
Bahde R, Kebschull L, Stoppeler S, Zibert A, Siaj R, Holzen J, et al.
Liver Int . 2011 Apr; 31(5):642-55. PMID: 21457437
Background: The regeneration capacity of cirrhotic livers might be affected by angiotensin-1 (AT1) receptors located on hepatic stellate cells (HSC). The effect of AT1 receptor blockade on microcirculation, fibrosis and...