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Hans-Georg Wirsching

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Articles 48
Citations 1960
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Recent Articles
1.
Velz J, Freudenmann L, Medici G, Dubbelaar M, Mohme M, Ghasemi D, et al.
Nat Commun . 2025 Feb; 16(1):1364. PMID: 39904979
Medulloblastoma is the most frequent malignant primary brain tumor in children. Despite recent advances in integrated genomics, the prognosis in children with high-risk medulloblastoma remains devastating, and new tumor-specific therapeutic...
2.
Sahm F, Bertero L, Brandner S, Capper D, Goldbrunner R, Jenkinson M, et al.
Neuro Oncol . 2024 Nov; PMID: 39577862
Meningiomas are the most common primary intracranial tumors of adults. For meningiomas that progress or recur despite surgical resection and radiotherapy, additional treatment options are limited due to lack of...
3.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, et al.
Genes Dev . 2024 Apr; 38(5-6):273-288. PMID: 38589034
Glioblastoma is universally fatal and characterized by frequent chromosomal copy number alterations harboring oncogenes and tumor suppressors. In this study, we analyzed exome-wide human glioblastoma copy number data and found...
4.
Stadler C, Gramatzki D, Le Rhun E, Hottinger A, Hundsberger T, Roelcke U, et al.
Neurooncol Pract . 2024 Mar; 11(2):132-141. PMID: 38496908
Background: Incidence rates of glioblastoma in very old patients are rising. The standard of care for this cohort is only partially defined and survival remains poor. The aims of this...
5.
Mastall M, Roth P, Bink A, Maranta A, Laubli H, Hottinger A, et al.
BMC Cancer . 2024 Jan; 24(1):82. PMID: 38225589
Background: Glioblastoma is the most common and most aggressive malignant primary brain tumor in adults. Glioblastoma cells synthesize and secrete large quantities of the excitatory neurotransmitter glutamate, driving epilepsy, neuronal...
6.
Padevit L, Vasella F, Friedman J, Mutschler V, Jenkins F, Held U, et al.
Front Oncol . 2023 Nov; 13:1279933. PMID: 38023177
Purpose: The selection of patients for further therapy after meningioma surgery remains a challenge. Progress has been made in this setting in selecting patients that are more likely to have...
7.
Wirsching H, Felsberg J, Prummer M, Moisoiu V, Lourman R, Hertler C, et al.
Acta Neuropathol . 2023 Aug; 146(4):647-649. PMID: 37573572
No abstract available.
8.
Wirsching H, Weller M
Adv Exp Med Biol . 2023 Jul; 1416:225-234. PMID: 37432631
Systemic treatment approaches are urgently needed for a subset of meningioma patients who do not achieve local tumor control with surgery and radiotherapy. Classical chemotherapy or anti-angiogenic agents exert only...
9.
Medici G, Freudenmann L, Velz J, Wang S, Kapolou K, Paramasivam N, et al.
Acta Neuropathol . 2023 Jun; 146(2):173-190. PMID: 37368072
Meningiomas are the most common primary intracranial tumors. Although most symptomatic cases can be managed by surgery and/or radiotherapy, a relevant number of patients experience an unfavorable clinical course and...
10.
Hertler C, Seystahl K, Le Rhun E, Wirsching H, Roth P, Weller M, et al.
Neuro Oncol . 2022 Jul; 24(11):2001-2004. PMID: 35906902
No abstract available.