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Hannah Spitzer

Explore the profile of Hannah Spitzer including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 438
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Recent Articles
1.
Ripart M, Spitzer H, Williams L, Walger L, Chen A, Napolitano A, et al.
JAMA Neurol . 2025 Feb; PMID: 39992650
Importance: A leading cause of surgically remediable, drug-resistant focal epilepsy is focal cortical dysplasia (FCD). FCD is challenging to visualize and often considered magnetic resonance imaging (MRI) negative. Existing automated...
2.
Asani B, Holmberg O, Schiefelbein J, Hafner M, Herold T, Spitzer H, et al.
Eye (Lond) . 2024 Jul; 38(16):3180-3186. PMID: 39068248
Objectives: To determine real-life quantitative changes in OCT biomarkers in a large set of treatment naive patients in a real-life setting undergoing anti-VEGF therapy. For this purpose, we devised a...
3.
Simats A, Zhang S, Messerer D, Chong F, Beskardes S, Sharma Chivukula A, et al.
Cell . 2024 Jul; 187(17):4637-4655.e26. PMID: 39043180
The medical burden of stroke extends beyond the brain injury itself and is largely determined by chronic comorbidities that develop secondarily. We hypothesized that these comorbidities might share a common...
4.
Frishberg A, Milman N, Alpert A, Spitzer H, Asani B, Schiefelbein J, et al.
Nat Commun . 2023 Oct; 14(1):6840. PMID: 37891175
Diseases change over time, both phenotypically and in their underlying molecular processes. Though understanding disease progression dynamics is critical for diagnostics and treatment, capturing these dynamics is difficult due to...
5.
Spitzer H, Berry S, Donoghoe M, Pelkmans L, Theis F
Nat Methods . 2023 May; 20(7):1058-1069. PMID: 37248388
Highly multiplexed imaging holds enormous promise for understanding how spatial context shapes the activity of the genome and its products at multiple length scales. Here, we introduce a deep learning...
6.
Spitzer H, Ripart M, Whitaker K, DArco F, Mankad K, Chen A, et al.
Brain . 2022 Aug; 145(11):3859-3871. PMID: 35953082
One outstanding challenge for machine learning in diagnostic biomedical imaging is algorithm interpretability. A key application is the identification of subtle epileptogenic focal cortical dysplasias (FCDs) from structural MRI. FCDs...
7.
Palla G, Spitzer H, Klein M, Fischer D, Schaar A, Kuemmerle L, et al.
Nat Methods . 2022 Feb; 19(2):171-178. PMID: 35102346
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of...
8.
Way G, Spitzer H, Burnham P, Raj A, Theis F, Singh S, et al.
Pac Symp Biocomput . 2021 Dec; 27:407-411. PMID: 34890168
Software has provided cell biologists the power to quantify specific cellular features in cell images at scale. Before long, these biologists also recognized the potential to extract much more biological...
9.
Schiffer C, Spitzer H, Kiwitz K, Unger N, Wagstyl K, Evans A, et al.
Neuroimage . 2021 Jul; 240:118327. PMID: 34224853
Human brain atlases provide spatial reference systems for data characterizing brain organization at different levels, coming from different brains. Cytoarchitecture is a basic principle of the microstructural organization of the...
10.
Spaulding S, Ansari E, Xing M, Sandler M, OMalley Q, Ho R, et al.
Am J Otolaryngol . 2021 Apr; 42(5):103003. PMID: 33894689
Background: Pharyngoesophageal stenosis (PES) is a serious complication that substantially impacts functional outcomes and quality of life (QOL) for up to a third of head and neck cancer patients who...