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Hannah S Heil

Explore the profile of Hannah S Heil including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 86
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Recent Articles
1.
Morgado L, Gomez-de-Mariscal E, Heil H, Henriques R
J Microsc . 2024 Mar; 295(2):85-92. PMID: 38445705
Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field of view and phototoxicity. To overcome these limitations,...
2.
Laine R, Heil H, Coelho S, Nixon-Abell J, Jimenez A, Wiesner T, et al.
Nat Methods . 2023 Nov; 20(12):1949-1956. PMID: 37957430
Live-cell super-resolution microscopy enables the imaging of biological structure dynamics below the diffraction limit. Here we present enhanced super-resolution radial fluctuations (eSRRF), substantially improving image fidelity and resolution compared to...
3.
Appeltshauser L, Linke J, Heil H, Karus C, Schenk J, Hemmen K, et al.
Neurobiol Dis . 2023 May; 182:106139. PMID: 37146836
The node of Ranvier is the key element in saltatory conduction along myelinated axons, but its specific protein organization remains elusive in the human species. To shed light on nanoscale...
4.
Mendes A, Heil H, Coelho S, Leterrier C, Henriques R
Open Biol . 2022 Jul; 12(7):220079. PMID: 35892200
Understanding the structure of supramolecular complexes provides insight into their functional capabilities and how they can be modulated in the context of disease. Super-resolution microscopy (SRM) excels in performing this...
5.
Korovesi A, Morgado L, Fumasoni M, Henriques R, Heil H, Del Rosario M
MicroPubl Biol . 2022 Jun; 2022. PMID: 35647499
The unicellular eukaryote is an invaluable resource for the study of basic eukaryotic cellular and molecular processes. However, its small size compared to other eukaryotic organisms the study of subcellular...
6.
Heil H, Aigner M, Maier S, Gupta P, Evers L, Gob V, et al.
Platelets . 2022 Feb; 33(6):849-858. PMID: 35109754
Interrogating platelets and their densely packed, highly abundant receptor landscape is key to understand platelet clotting, a process that can save lives when stopping blood loss after an injury, but...
7.
Del Rosario M, Heil H, Mendes A, Saggiomo V, Henriques R
Adv Biol (Weinh) . 2021 Oct; 6(4):e2100994. PMID: 34693666
The maker movement has reached the optics labs, empowering researchers to create and modify microscope designs and imaging accessories. 3D printing has a disruptive impact on the field, improving accessibility...
8.
Emperle M, Bangalore D, Adam S, Kunert S, Heil H, Heinze K, et al.
Nucleic Acids Res . 2021 Jul; 49(14):8294-8308. PMID: 34289056
DNMT3A/3L heterotetramers contain two active centers binding CpG sites at 12 bp distance, however their interaction with DNA not containing this feature is unclear. Using randomized substrates, we observed preferential...
9.
Bangalore D, Heil H, Mehringer C, Hirsch L, Hemmen K, Heinze K, et al.
Sci Rep . 2020 Sep; 10(1):15484. PMID: 32968112
Base excision repair is the dominant DNA repair pathway of chemical modifications such as deamination, oxidation, or alkylation of DNA bases, which endanger genome integrity due to their high mutagenic...
10.
Volz J, Kusch C, Beck S, Popp M, Vogtle T, Meub M, et al.
J Clin Invest . 2020 Aug; 130(11):6064-6079. PMID: 32750041
Store-operated Ca2+ entry (SOCE) is the major route of Ca2+ influx in platelets. The Ca2+ sensor stromal interaction molecule 1 (STIM1) triggers SOCE by forming punctate structures with the Ca2+...