Hannah L Hertz
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Explore the profile of Hannah L Hertz including associated specialties, affiliations and a list of published articles.
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7
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39
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Recent Articles
1.
Wang Y, Hertz H, Pastore B, Tang W
Nucleic Acids Res
. 2025 Feb;
53(4).
PMID: 39970287
In all three domains of life, genes with related functions can be organized into specific genomic regions known as gene clusters. In eukaryotes, histone, piRNA (Piwi-interacting RNA), and rDNA (ribosomal...
2.
Wang Y, Hertz H, Pastore B, Tang W
Nucleic Acids Res
. 2025 Feb;
53(4).
PMID: 39945323
In all three domains of life, genes with related functions can be organized into specific genomic regions known as gene clusters. In eukaryotes, histone, piRNA (Piwi-interacting RNA), and rDNA (ribosomal...
3.
Pastore B, Hertz H, Tang W
Cell Rep
. 2024 Jan;
43(2):113692.
PMID: 38244197
The Piwi/Piwi-interacting RNA (piRNA) pathway protects genome integrity in animal germ lines. Maturation of piRNAs involves nucleolytic processing at both 5' and 3' ends. The ribonuclease PARN-1 and its orthologs...
4.
Pastore B, Hertz H, Tang W
bioRxiv
. 2023 Oct;
PMID: 37808652
In animal germ lines, The Piwi/piRNA pathway plays a crucial role in safeguarding genome integrity and promoting fertility. Following transcription from discrete genomic loci, piRNA precursors undergo nucleolytic processing at...
5.
Price I, Wagner J, Pastore B, Hertz H, Tang W
Nat Commun
. 2023 Sep;
14(1):5965.
PMID: 37749091
Germ granules are membrane-less organelles essential for small RNA biogenesis and germline development. Among the conserved properties of germ granules is their association with the nuclear membrane. Recent studies demonstrated...
6.
Pastore B, Hertz H, Tang W
RNA Biol
. 2022 Nov;
19(1):1276-1292.
PMID: 36412988
Piwi proteins and Piwi-interacting RNAs (piRNAs) are best known for their roles in suppressing transposons and promoting fertility. Yet piRNA biogenesis and its mechanisms of action differ widely between distantly...
7.
Hertz H, Price I, Tang W
Bio Protoc
. 2022 Jul;
12(8):e4386.
PMID: 35800092
Membraneless organelles, such as germ granules and stress granules, are liquid-like condensates formed by phase transition. Recently, we and others have adopted proximity-based labeling methods to determine the composition of...
8.
Price I, Hertz H, Pastore B, Wagner J, Tang W
Elife
. 2021 Nov;
10.
PMID: 34730513
The germ line produces gametes that transmit genetic and epigenetic information to the next generation. Maintenance of germ cells and development of gametes require germ granules-well-conserved membraneless and RNA-rich organelles....
9.
pre-piRNA trimming and 2'-O-methylation protect piRNAs from 3' tailing and degradation in C. elegans
Pastore B, Hertz H, Price I, Tang W
Cell Rep
. 2021 Sep;
36(9):109640.
PMID: 34469728
The Piwi-interacting RNA (piRNA) pathway suppresses transposable elements and promotes fertility in diverse organisms. Maturation of piRNAs involves pre-piRNA trimming followed by 2'-O-methylation at their 3' termini. Here, we report...