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Hangyu Chen

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Recent Articles
1.
Kuerban S, Chen H, Chen L, Zhang L, Li X, Zhen B, et al.
World J Surg Oncol . 2025 Mar; 23(1):90. PMID: 40089765
Background: A blood-based approach to monitor metastasis and recurrence of esophageal squamous cell carcinoma (ESCC) remains undeveloped. This study aimed to establish a dependable model utilizing cfDNA 5-hydroxymethylcytosines (5hmC) signatures...
2.
Zhang L, Duolikun M, Chen H, Wang Z, Li X, Xiao H, et al.
Sci Rep . 2025 Feb; 15(1):6165. PMID: 39979392
Ischemia-reperfusion injury (IRI) is one of the leading causes of mortality and disability worldwide. Owing to its complex pathogenesis, there is still a lack of effective therapeutic targets in clinical...
3.
Xu N, Gao Z, Wu D, Chen H, Zhang Z, Zhang L, et al.
Clin Transl Med . 2025 Feb; 15(2):e70189. PMID: 39956959
Metachronous liver metastases (MLM) are characterised by high incidence and high mortality in clinical colorectal cancer treatment. Currently traditional clinical methods cannot effectively predict and prevent the occurrence of metachronous...
4.
Xie W, Li X, Chen H, Chu J, Zhang L, Tang B, et al.
Cancer Med . 2024 Dec; 13(24):e70477. PMID: 39711442
Background: An effective urine-based method for the diagnosis, differential diagnosis and prognosis of multiple myeloma (MM) has not yet been developed. Urine cell-free DNA (cfDNA) carrying cancer-specific genetic and epigenetic...
5.
Chen H, Duolikun M, Zhu H
Front Cell Dev Biol . 2024 Dec; 12:1387959. PMID: 39620143
Background: 5-Hydroxymethylcytosine (5hmC) is an important DNA epigenetic modification that plays a vital role in tumorigenesis, progression and prognosis. Previous studies have shown that it plays an important role in...
6.
Li G, Zhang R, Chen K, Dong J, Yang Z, Chen H, et al.
Biomaterials . 2024 Nov; 315:122912. PMID: 39490059
Stroke is one of the leading causes of death and disability in the world. Ischemic stroke causes overproduction of reactive oxygen/nitrogen species (RONS) after reperfusion, triggering inflammatory responses that further...
7.
Ta X, Wang B, Bai J, Yu J, Chen H, Wang C
Food Chem . 2024 Aug; 461:140791. PMID: 39163721
Stachyose is a new functional oligosaccharide that exists naturally in plants, including Stachys sieboldii and Rehmannia glutinosa. Because of its low sweetness, low-calorie content, and robust stability, it has been...
8.
Xiao H, Chen H, Zhang L, Duolikun M, Zhen B, Kuerban S, et al.
World J Surg Oncol . 2024 Jun; 22(1):152. PMID: 38849867
Background: Although sorafenib has been consistently used as a first-line treatment for advanced hepatocellular carcinoma (HCC), most patients will develop resistance, and the mechanism of resistance to sorafenib needs further...
9.
Huang H, Ge L, Zhang X, Chen H, Shen Y, Xiao J, et al.
Chemosphere . 2023 Dec; 349:140813. PMID: 38040254
Heavy metal (HM) pollution has extensively spread in agricultural soils, posing potential threats to food safety and human health. Biochar and lime are two amendments used to remediate the soils...
10.
Chen L, Ren A, Zhao Y, Chen H, Wu Q, Zheng M, et al.
J Hematol Oncol . 2023 Nov; 16(1):113. PMID: 37993905
T-cell acute lymphoblastic leukemia (T-ALL) is a type of hematologic tumor with malignant proliferation of hematopoietic progenitor cells. However, traditional clinical treatment of T-ALL included chemotherapy and stem cell transplantation...