Hana Bruchova
Overview
Explore the profile of Hana Bruchova including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
387
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Recent Articles
1.
Merkerova M, Vasikova A, Bruchova H, Libalova H, Topinka J, Balascak I, et al.
Eur J Haematol
. 2009 Jun;
83(3):183-90.
PMID: 19500137
Objectives: Umbilical cord blood (UCB) has become a useful alternative source of hematopoietic stem cells for clinical and research applications. UCB represents neonatal blood and differs from adult blood in...
2.
Merkerova M, Vasikova A, Belickova M, Bruchova H
Stem Cells Dev
. 2009 May;
19(1):17-26.
PMID: 19435428
MicroRNAs (miRNAs), important regulators of cellular processes, show specific expression signatures in different blood cell lineages and stages of hematopoietic stem cell (HSC) differentiation, indicating their role in the control...
3.
Bruchova H, Yoon D, Agarwal A, Swierczek S, Prchal J
Blood Cells Mol Dis
. 2009 Mar;
43(1):81-7.
PMID: 19264517
Polycythemia vera (PV) is an acquired myeloproliferative clonal disorder, characterized by augmented erythropoiesis. To better define PV pathogenesis, we performed an in vitro erythroid expansion from peripheral blood mononuclear cells...
4.
Kracmarova A, cermak J, Brdicka R, Bruchova H
Leuk Lymphoma
. 2008 Jul;
49(7):1297-305.
PMID: 18604718
Myelodysplastic syndrome (MDS) represents a good model for research of prognostic/progression markers due to frequent transformation into acute myeloid leukemia (AML). We analysed expression profiles of 26 MDS and 6...
5.
Merkerova M, Belickova M, Bruchova H
Eur J Haematol
. 2008 Jun;
81(4):304-10.
PMID: 18573170
Objectives: MicroRNAs (miRNAs) play key roles in a wide variety of normal and pathological cellular processes. A number of studies identified hematopoietic-specific miRNAs that are necessary for correct function of...
6.
Bruchova H, Merkerova M, Prchal J
Haematologica
. 2008 May;
93(7):1009-16.
PMID: 18508790
Background: Polycythemia vera is a clonal hematopoietic stem cell disorder in which the JAK2 V617F mutation is observed in >95% of patients, but an as yet unidentified process appears to...
7.
Bruchova H, Yoon D, Agarwal A, Mendell J, Prchal J
Exp Hematol
. 2007 Nov;
35(11):1657-67.
PMID: 17976518
Objective: Polycythemia vera (PV) is a myeloproliferative disorder, arising from the acquired mutation(s) of a hematopoietic stem cell. The JAK2 V617F somatic mutation is found in most PV patients; however,...
8.
Merkerova M, Bruchova H, Kracmarova A, Klamova H, Brdicka R
Leuk Lymphoma
. 2007 Apr;
48(4):793-801.
PMID: 17454639
It has been demonstrated that over-expression of Bmi-1 occurs in a variety of cancers, including several types of leukemia. This gene plays a key role in the self-renewal of stem...
9.
Merkerova M, Klamova H, Brdicka R, Bruchova H
Mol Biol Rep
. 2006 Nov;
34(1):27-33.
PMID: 17094012
Development of array methods contributes to elucidation of many genes expressed during oncogenesis. Our array-based analyses of gene expression in patients with chronic myeloid leukemia (CML) revealed several genes (MMP8,...
10.
Merkerova M, Bruchova H, Brdicka R
Leuk Res
. 2006 Oct;
31(5):661-72.
PMID: 17070905
Imatinib metylase is the first choice treatment for BCR/ABL positive chronic myelogenous leukemia (CML). However, as some CML patients develop resistance to imatinib therapy, there is a significant interest in...