Hailiang Hu
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Explore the profile of Hailiang Hu including associated specialties, affiliations and a list of published articles.
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85
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1202
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Recent Articles
1.
Huang Y, Chen Z, Deng W, Jiang Y, Pan Y, Yuan Z, et al.
Cell Death Dis
. 2025 Mar;
16(1):173.
PMID: 40075073
Mohr-Tranebjaerg syndrome (MTS) is a rare X-linked recessive neurodegenerative disorder caused by mutations in the Translocase of Inner Mitochondrial Membrane 8A (TIMM8A) gene, which encodes TIMM8a, a protein localized to...
2.
Cheng B, Li M, Zheng J, Liang J, Li Y, Liang R, et al.
Nat Chem Biol
. 2025 Jan;
PMID: 39789191
Cell surface receptor-targeted protein degraders hold promise for drug discovery. However, their application is restricted because of the complexity of creating bifunctional degraders and the reliance on specific lysosome-shuttling receptors...
3.
Chen Y, Gong S, Tang J, Wang X, Gao Y, Yang H, et al.
Stem Cell Rev Rep
. 2024 Nov;
21(2):509-519.
PMID: 39560864
Genetic variations of signaling modulator protein LNK (also called SH2B3) are associated with relatively mild myeloproliferative phenotypes in patients with myeloproliferative neoplasms (MPN). However, these variations can induce more severe...
4.
Gao D, Shen Y, Xu L, Sun Y, Hu H, Xu B, et al.
Drug Resist Updat
. 2024 Oct;
77:101158.
PMID: 39395327
Aims: Tumor fatty acid (FA) metabolic plasticity plays a pivotal role in resistance to therapy and poses limitations to anticancer strategies. In this study, our aim is to uncover the...
5.
Huang Y, Wang Q, Zhou W, Jiang Y, He K, Huang W, et al.
Neoplasia
. 2024 Oct;
57:101054.
PMID: 39366214
Aberrant expression of cyclin-dependent kinase 5 (Cdk5) has been reported in pituitary adenomas. However, the role of Cdk5 in the tumorigenesis remains unclear. We show that prenatal p25-activated Cdk5 phosphorylates...
6.
Hou X, Hu H, Kong C, Zhang S, Wang W, Lu S
BMC Musculoskelet Disord
. 2024 Aug;
25(1):659.
PMID: 39169374
Background: Morphometric analysis of the psoas major muscle has shown utility in predicting postoperative morbidity in various surgical fields, but its usefulness in predicting complications in elderly patients undergoing multilevel...
7.
Zhang H, Zhou Y, Feng Y, Hou W, Chen Y, Xing Z, et al.
Clin Transl Med
. 2024 May;
14(5):e1678.
PMID: 38736108
Background: Cyclin-dependent kinase 12 (CDK12)-deficient prostate cancer defines a subtype of castration-resistant prostate cancer (CRPC) with a poor prognosis. Current therapy, including PARP inhibitors, shows minimal treatment efficacy for this...
8.
Wang Z, Zhang J, Wang Y, Zhou J, Jiao X, Han M, et al.
ACS Nano
. 2024 Mar;
18(14):10324-10340.
PMID: 38547369
A major challenge in using nanocarriers for intracellular drug delivery is their restricted capacity to escape from endosomes into the cytosol. Here, we significantly enhance the drug delivery efficiency by...
9.
Hong Y, Zuo S, Du H, Shi Z, Hu H, Li G
ACS Appl Mater Interfaces
. 2024 Mar;
16(11):13745-13755.
PMID: 38446712
Currently, it is still a challenge to directly achieve highly stable metal-organic frameworks (MOFs) with superior proton conductivity solely through the exquisite design of ligands and the attentive selection of...
10.
Hou X, Hu H, Cui P, Kong C, Wang W, Lu S
BMC Surg
. 2024 Feb;
24(1):59.
PMID: 38365668
Objective: To identify the predictors for the achievement of minimal clinically important difference (MCID) in functional status among elderly patients with degenerative lumbar spinal stenosis (DLSS) undergoing lumbar decompression and...