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Hai Yang Hu

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Articles 8
Citations 645
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Recent Articles
1.
Yin Y, Lu J, Zhou Y, Shi L, Yuan D, Chen J, et al.
Biomed Environ Sci . 2021 Jun; 34(5):400-403. PMID: 34059178
No abstract available.
2.
Hu H, He L, Khaitovich P
BMC Genomics . 2014 Jun; 15:457. PMID: 24916849
Background: Comprehensive annotation of transcripts expressed in a given tissue is a critical step towards the understanding of regulatory and functional pathways that shape the transcriptome. Results: Here, we reconstructed...
3.
Hu H, He L, Fominykh K, Yan Z, Guo S, Zhang X, et al.
Nat Commun . 2012 Oct; 3:1145. PMID: 23093182
MicroRNA-mediated gene regulation is important in many physiological processes. Here we explore the roles of a microRNA, miR-941, in human evolution. We find that miR-941 emerged de novo in the...
4.
Hu H, Guo S, Xi J, Yan Z, Fu N, Zhang X, et al.
PLoS Genet . 2011 Oct; 7(10):e1002327. PMID: 22022286
Among other factors, changes in gene expression on the human evolutionary lineage have been suggested to play an important role in the establishment of human-specific phenotypes. However, the molecular mechanisms...
5.
Yan Z, Hu H, Jiang X, Maierhofer V, Neb E, He L, et al.
Nucleic Acids Res . 2011 May; 39(15):6596-607. PMID: 21546553
Piwi-interacting RNA (piRNA) are small RNA abundant in the germline across animal species. In fruit flies and mice, piRNA have been implicated in maintenance of genomic integrity by transposable elements...
6.
Somel M, Guo S, Fu N, Yan Z, Hu H, Xu Y, et al.
Genome Res . 2010 Jul; 20(9):1207-18. PMID: 20647238
Changes in gene expression levels determine differentiation of tissues involved in development and are associated with functional decline in aging. Although development is tightly regulated, the transition between development and...
7.
Shao N, Hu H, Yan Z, Xu Y, Hu H, Menzel C, et al.
BMC Genomics . 2010 Jul; 11:409. PMID: 20591156
Background: MicroRNA (miRNA) play an important role in gene expression regulation. At present, the number of annotated miRNA continues to grow rapidly, in part due to advances of high-throughput sequencing...
8.
Hu H, Yan Z, Xu Y, Hu H, Menzel C, Zhou Y, et al.
BMC Genomics . 2009 Sep; 10:413. PMID: 19732433
Background: During microRNA (miRNA) maturation in humans and flies, Drosha and Dicer cut the precursor transcript, thereby producing a short RNA duplex. One strand of this duplex becomes a functional...