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Hae-Seong Yoon

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Articles 9
Citations 105
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Recent Articles
1.
Kim D, Lee Y, Ryu H, Lee J, Kim H, Kim E, et al.
J Appl Toxicol . 2011 Dec; 33(1):63-70. PMID: 22131055
Heterocyclic amines (HCAs) are naturally produced during common cooking processes for meats and fish. HCAs are metabolized by various enzymes, including cytochromes P450, N-acetyl transferases, and sulfotransferases, and their bioactivated...
2.
Shin B, Hwang S, Bulitta J, Lee J, Yang S, Park J, et al.
J Toxicol Environ Health A . 2010 Oct; 73(21-22):1586-98. PMID: 20954083
The objective of this study was to predict the exposure to bisphenol A (BPA) after oral intake in human blood and tissues using physiologically based pharmacokinetic (PBPK) modeling. A refined...
3.
Shin B, Hong S, Bulitta J, Hwang S, Kim H, Lee J, et al.
J Toxicol Environ Health A . 2010 Jan; 72(21-22):1406-11. PMID: 20077212
This study was conducted to characterize the disposition, oral bioavailability, and tissue distribution of zearalenone in rats. The pharmacokinetics and tissue distribution of zearalenone were studied after intravenous (i.v.) or...
4.
Shin B, Hong S, Bulitta J, Lee J, Hwang S, Kim H, et al.
J Toxicol Environ Health A . 2010 Jan; 72(21-22):1395-405. PMID: 20077211
The objectives of this study were to (1) develop physiologically based pharmacokinetic (PBPK) models for zearalenone following intravenous (i.v.) and oral (p.o.) dosing in rats and (2) predict concentrations in...
5.
Shin B, Hong S, Hwang S, Kim H, Lee J, Yoon H, et al.
Biomed Chromatogr . 2009 Apr; 23(9):1014-21. PMID: 19347967
Zearalenone, a mycotoxin biosynthesized by various Fusarium fungi, is widely found as a contaminant in grains and animal feeds. This study describes a rapid and sensitive LC/MS/MS assay method for...
6.
Lee Y, Ryu H, Kim H, Min C, Lee J, Kim E, et al.
Reprod Toxicol . 2008 Jun; 25(4):413-9. PMID: 18577445
Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during...
7.
Yoon H, Ramachandiran S, Chacko M, Monks T, Lau S
Am J Physiol Renal Physiol . 2003 Nov; 286(2):F417-24. PMID: 14612383
The tuberous sclerosis-2 (Tsc-2) gene is a suppressor of renal tumorigenesis and an early target of reactive oxygen species-induced renal cancer. Tuberin, the protein product of the Tsc-2 gene, participates...
8.
Snyderwine E, Yoon H, Tran M, Schut H, Yu M
Mutagenesis . 2002 Dec; 18(1):7-12. PMID: 12473729
2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a mutagen and rodent mammary gland carcinogen found in the human diet. 2-Hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-hydroxy-PhIP) is the proximate reactive metabolite of PhIP associated with PhIP-DNA adduct formation and...
9.
Yoon H, Monks T, Everitt J, Walker C, Lau S
Am J Physiol Renal Physiol . 2002 Jul; 283(2):F262-70. PMID: 12110509
Although 2,3,5-tris-(glutathion-S-yl)hydroquinone (TGHQ; 2.5 micromol/kg ip) markedly increased cell proliferation within the outer stripe of the outer medulla (OSOM) of the kidney in both wild-type (Tsc2(+/+)) and mutant Eker rats...