Hadir Marei
Overview
Explore the profile of Hadir Marei including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
246
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kschonsak Y, Gao X, Miller S, Hwang S, Marei H, Wu P, et al.
Cell Chem Biol
. 2023 Dec;
31(6):1176-1187.e10.
PMID: 38056465
Selective and precise activation of signaling transduction cascades is key for cellular reprogramming and tissue regeneration. However, the development of small- or large-molecule agonists for many signaling pathways has remained...
2.
Marei H, Tsai W, Kee Y, Ruiz K, He J, Cox C, et al.
Nature
. 2022 Sep;
610(7930):182-189.
PMID: 36131013
Most current therapies that target plasma membrane receptors function by antagonizing ligand binding or enzymatic activities. However, typical mammalian proteins comprise multiple domains that execute discrete but coordinated activities. Thus,...
3.
Yuki K, Marei H, Fiskin E, Eva M, Gopal A, Schwartzentruber J, et al.
Nat Microbiol
. 2019 Jul;
4(9):1516-1531.
PMID: 31285585
Salmonella presents a global public health concern. Central to Salmonella pathogenicity is an ability to subvert host defences through strategically targeting host proteins implicated in restricting infection. Therefore, to gain...
4.
Marei H, Malliri A
Small GTPases
. 2016 Jul;
8(3):139-163.
PMID: 27442895
Abnormal Rac1 signaling is linked to a number of debilitating human diseases, including cancer, cardiovascular diseases and neurodegenerative disorders. As such, Rac1 represents an attractive therapeutic target, yet the search...
5.
Marei H, Malliri A
Small GTPases
. 2016 Jun;
8(2):90-99.
PMID: 27314616
GEFs play a critical role in regulating Rac1 signaling. They serve as signaling nodes converting upstream signals into downstream Rac1-driven cellular responses. Through associating with membrane-bound Rac1, GEFs facilitate the...
6.
Marei H, Carpy A, Macek B, Malliri A
Cell Cycle
. 2016 May;
15(15):1961-74.
PMID: 27152953
The small GTPase Rac1 is implicated in various cellular processes that are essential for normal cell function. Deregulation of Rac1 signaling has also been linked to a number of diseases,...
7.
Marei H, Carpy A, Woroniuk A, Vennin C, White G, Timpson P, et al.
Nat Commun
. 2016 Feb;
7:10664.
PMID: 26887924
The small GTPase Rac1 has been implicated in the formation and dissemination of tumours. Upon activation by guanine nucleotide exchange factors (GEFs), Rac1 associates with a variety of proteins in...