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Haden L Scott

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Articles 27
Citations 422
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Recent Articles
1.
Tan L, Scott H, Smith M, Pingali S, Cheng X, ONeill H, et al.
Langmuir . 2025 Jan; 41(2):1281-1296. PMID: 39772768
Solvent toxicity limits -butanol fermentation titer, increasing the cost and energy consumption for subsequent separation processes and making biobased production more expensive and energy-intensive than petrochemical approaches. Amphiphilic solvents such...
2.
Scott H, Burns-Casamayor V, Dixson A, Standaert R, Stanley C, Stingaciu L, et al.
Biochim Biophys Acta Biomembr . 2024 May; 1866(7):184349. PMID: 38815687
Cell membranes are responsible for a range of biological processes that require interactions between lipids and proteins. While the effects of lipids on proteins are becoming better understood, our knowledge...
3.
Scott H, Bolmatov D, Premadasa U, Doughty B, Carrillo J, Sacci R, et al.
ACS Appl Mater Interfaces . 2023 Sep; 15(37):44533-44540. PMID: 37696028
Phospholipid bilayers can be described as capacitors whose capacitance per unit area (specific capacitance, ) is determined by their thickness and dielectric constant─independent of applied voltage. It is also widely...
4.
McClintic W, Scott H, Moore N, Farahat M, Maxwell M, Schuman C, et al.
MRS Bull . 2023 Mar; 48(1):13-21. PMID: 36908998
Abstract: In biology, heterosynaptic plasticity maintains homeostasis in synaptic inputs during associative learning and memory, and initiates long-term changes in synaptic strengths that nonspecifically modulate different synapse types. In bioinspired...
5.
Kinnun J, Scott H, Bolmatov D, Collier C, Charlton T, Katsaras J
Biophys J . 2023 Jan; 122(6):931-949. PMID: 36698312
For the past 50 years, evidence for the existence of functional lipid domains has been steadily accumulating. Although the notion of functional lipid domains, also known as "lipid rafts," is...
6.
Heberle F, Welsch D, Scott H, Waxham M
Biophys Rep (N Y) . 2023 Jan; 3(1):100090. PMID: 36593976
Cryogenic electron microscopy (cryo-EM) is among the most powerful tools available for interrogating nanoscale structure of biological materials. We recently showed that cryo-EM can be used to measure the bilayer...
7.
Kangarlou B, Hoy D, Scott H, Pingali S, Khalil N, Chung B, et al.
Langmuir . 2022 Dec; 39(1):227-235. PMID: 36580910
The amount of water in therapeutic nanoparticles (NPs) is of great importance to the pharmaceutical industry, as water content reflects the volume occupied by the solid components. For example, certain...
8.
Scott H, Bolmatov D, Podar P, Liu Z, Kinnun J, Doughty B, et al.
Proc Natl Acad Sci U S A . 2022 Dec; 119(50):e2212195119. PMID: 36469762
Biological supramolecular assemblies, such as phospholipid bilayer membranes, have been used to demonstrate signal processing via short-term synaptic plasticity (STP) in the form of paired pulse facilitation and depression, emulating...
9.
Semeraro E, Marx L, Mandl J, Letofsky-Papst I, Mayrhofer C, Frewein M, et al.
Elife . 2022 Jun; 11. PMID: 35670565
We report the real-time response of to lactoferricin-derived antimicrobial peptides (AMPs) on length scales bridging microscopic cell sizes to nanoscopic lipid packing using millisecond time-resolved synchrotron small-angle X-ray scattering. Coupling...
10.
Frewein M, Doktorova M, Heberle F, Scott H, Semeraro E, Porcar L, et al.
Symmetry (Basel) . 2022 May; 13(8). PMID: 35530371
We addressed the frequent occurrence of mixed-chain lipids in biological membranes and their impact on membrane structure by studying several chain-asymmetric phosphatidylcholines and the highly asymmetric milk sphingomyelin. Specifically, we...