Haakon B Nygaard
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Explore the profile of Haakon B Nygaard including associated specialties, affiliations and a list of published articles.
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40
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3232
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Recent Articles
1.
Ahdi A, Ensworth A, Schulz B, MacMillan E, Mirian M, Vahabie A, et al.
Comput Biol Med
. 2025 Feb;
187:109806.
PMID: 39923591
Proton magnetic resonance spectroscopy (H-MRS) is a valuable non-invasive method for quantifying brain metabolites. Most MRS spectra are pre-processed by taking the mean of several single-acquisition transients, ultimately resulting in...
2.
Smith E, Phillips N, Feldman H, Borrie M, Ganesh A, Henri-Bhargava A, et al.
J Prev Alzheimers Dis
. 2025 Feb;
12(3):100068.
PMID: 39893139
Lecanemab and donanemab are monoclonal antibody therapies that remove amyloid-beta from the brain. They are the first therapies that alter a fundamental mechanism, amyloid-beta deposition, in Alzheimer disease (AD). To...
3.
Buonfiglioli A, Kubler R, Missall R, Jong R, Chan S, Haage V, et al.
Brain Behav Immun
. 2024 Nov;
123():1127-1146.
PMID: 39500415
Prenatal infections and activation of the maternal immune system have been proposed to contribute to causing neurodevelopmental disorders (NDDs), chronic conditions often linked to brain abnormalities. Microglia are the resident...
4.
Gabuzyan R, Lee C, Nygaard H
J Alzheimers Dis
. 2024 Oct;
101(s1):S443-S453.
PMID: 39422952
Dementia represents one of the largest and most urgent public health problems across the globe. Modeling projections have estimated that delaying the onset of Alzheimer's disease (AD) by 6 months...
5.
Buonfiglioli A, Kubler R, Missall R, Jong R, Chan S, Haage V, et al.
bioRxiv
. 2024 Jun;
PMID: 38826204
Prenatal infections and activation of the maternal immune system have been proposed to contribute to causing neurodevelopmental disorders (NDDs), chronic conditions often linked to brain abnormalities. Microglia are the resident...
6.
Patel K, Yang D, Best J, Chambers C, Lee P, Henri-Bhargava A, et al.
Alzheimers Dement (N Y)
. 2024 Apr;
10(2):e12464.
PMID: 38596484
Introduction: In the Investigating the Impact of Alzheimer's Disease Diagnostics in British Columbia (IMPACT-AD BC) study, we aimed to understand how Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker testing-used in...
7.
Patel K, Yang D, Feldman H, Hsiung G, Nygaard H, Best J, et al.
Alzheimers Dement (N Y)
. 2024 Apr;
10(2):e12463.
PMID: 38596482
Introduction: We described patients' and care partners' experiences with Alzheimer's disease (AD) cerebrospinal fluid (CSF) biomarker testing and result disclosure in routine care. Methods: IMPACT-AD BC is an observational study...
8.
Black S, Budd N, Nygaard H, Verret L, Virdi S, Tamblyn Watts L, et al.
Can J Neurol Sci
. 2023 Aug;
51(4):487-494.
PMID: 37593895
Background: Alzheimer's disease (AD) is experienced by > 600,000 Canadians. Disease-modifying therapies (DMTs) for earlier stages of disease are in development. Existing health system capacity constraints and the need for...
9.
Lee C, Frew J, Weilinger N, Wendt S, Cai W, Sorrentino S, et al.
Neurobiol Dis
. 2023 Apr;
181:106124.
PMID: 37054899
Frontotemporal dementia (FTD) refers to a group of neurodegenerative disorders that are characterized by pathology predominantly localized to the frontal and temporal lobes. Approximately 40% of FTD cases are familial,...
10.
Wendt S, Johnson S, Weilinger N, Groten C, Sorrentino S, Frew J, et al.
Redox Biol
. 2022 Aug;
56:102448.
PMID: 36037587
The inter-relationship between microglia dynamics and oxidative stress (Ox-stress) in dystrophic neurites (DNs) at Alzheimer's Disease (AD) plaques may contribute to the pathological changes in neurons. We developed new in...