H Widner
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Explore the profile of H Widner including associated specialties, affiliations and a list of published articles.
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Recent Articles
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Piccini P, Lindvall O, Bjorklund A, Brundin P, Hagell P, Ceravolo R, et al.
Ann Neurol
. 2000 Nov;
48(5):689-95.
PMID: 11079531
Intrastriatal transplantation of dopaminergic neurones aims to repair the selective loss of nigrostriatal projections and the consequent dysfunction of striatocortical circuitries in Parkinson's disease (PD). Here, we have studied the...
13.
Larsson L, Widner H
Scand J Immunol
. 2000 Sep;
52(3):249-56.
PMID: 10972900
Neural transplantation may become an important treatment alternative for focal brain disorders. To date, the most successful grafts have been obtained in patients with Parkinson's disease. Completely normalized dopamine production...
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Brevig T, Holgersson J, Widner H
Trends Neurosci
. 2000 Jul;
23(8):337-44.
PMID: 10906793
Neural transplantation holds promise for focal CNS repair. Owing to the shortage of human donor material, which is derived from aborted embryos, and ethical concerns over its use, animal donor...
17.
Brundin P, Pogarell O, Hagell P, Piccini P, Widner H, Schrag A, et al.
Brain
. 2000 Jun;
123 ( Pt 7):1380-90.
PMID: 10869050
Five parkinsonian patients were transplanted bilaterally into the putamen and caudate nucleus with human embryonic mesencephalic tissue from between seven and nine donors. To increase graft survival, the lipid peroxidation...
18.
Lundin S, Widner H
Lakartidningen
. 2000 May;
97(16):1940-3.
PMID: 10826351
Transplantation of neural tissue is an effective therapeutical approach in Parkinson's disease, but the method is constrained by the lack of suitable donor material. Embryonic neural tissue from pigs, xenografts,...
19.
Larsson L, Czech K, Brundin P, Widner H
Cell Transplant
. 2000 May;
9(2):261-72.
PMID: 10811398
Transplantation of neural tissue from other species has the potential to improve function in patients with neurodegenerative disorders. We investigated the functional effects of embryonic porcine dopaminergic neurons transplanted in...
20.
Barker R, Kendall A, Widner H
Cell Transplant
. 2000 May;
9(2):235-46.
PMID: 10811396
Embryonic allografted human tissue in patients with Parkinson's disease has been shown to survive and ameliorate many of the symptoms of this disease. Despite this success, the practical problems of...