H Westphal
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Explore the profile of H Westphal including associated specialties, affiliations and a list of published articles.
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175
Citations
10124
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Recent Articles
11.
Baudet C, Mikaels A, Westphal H, Johansen J, Johansen T, Ernfors P
Development
. 2000 Sep;
127(20):4335-44.
PMID: 11003834
Glial cell line-derived neurotrophic factor (GDNF), neurturin (NTN) and neublastin/artemin (ART) are distant members of the transforming growth factor beta family, and have been shown to elicit neurotrophic effects upon...
12.
Messer C, Eisch A, Carlezon Jr W, Whisler K, Shen L, Wolf D, et al.
Neuron
. 2000 May;
26(1):247-57.
PMID: 10798408
The present study examined a role for GDNF in adaptations to drugs of abuse. Infusion of GDNF into the ventral tegmental area (VTA), a dopaminergic brain region important for addiction,...
13.
Granholm A, Reyland M, Albeck D, Sanders L, Gerhardt G, Hoernig G, et al.
J Neurosci
. 2000 Apr;
20(9):3182-90.
PMID: 10777782
Glial cell line-derived neurotrophic factor (GDNF) is one of the most potent trophic factors that have been identified for midbrain dopamine (DA) neurons. Null mutations for trophic factor genes have...
14.
Mikaels A, Livet J, Westphal H, De Lapeyriere O, Ernfors P
Eur J Neurosci
. 2000 Mar;
12(2):446-56.
PMID: 10712625
Glial cell line-derived neurotrophic factor (GDNF) family ligands promote the survival of developing motor neurons in vivo and in vitro. However, not all neurons survive with any single ligand in...
15.
Birk O, Casiano D, Wassif C, Cogliati T, Zhao L, Zhao Y, et al.
Nature
. 2000 Mar;
403(6772):909-13.
PMID: 10706291
During mammalian embryonic development, the ovaries and testes develop from somatic cells of the urogenital ridges as indifferent gonads, harbouring primordial germ cells that have migrated there. After sex determination...
16.
Meng X, Lindahl M, Hyvonen M, Parvinen M, de Rooij D, Hess M, et al.
Science
. 2000 Feb;
287(5457):1489-93.
PMID: 10688798
The molecular control of self-renewal and differentiation of stem cells has remained enigmatic. Transgenic loss-of-function and overexpression models now show that the dosage of glial cell line-derived neurotrophic factor (GDNF),...
17.
Tomac A, Grinberg A, Huang S, Nosrat C, Wang Y, Borlongan C, et al.
Neuroscience
. 2000 Feb;
95(4):1011-23.
PMID: 10682708
Glial cell line-derived neurotrophic factor receptor alpha1 (GFRalpha1, also known as GDNFR-alpha) is a glycolipid-anchored membrane protein of the GFRalpha family, which binds glial cell line-derived neurotrophic factor [Jing S....
18.
19.
Hobert O, Westphal H
Trends Genet
. 2000 Feb;
16(2):75-83.
PMID: 10652534
Homeobox genes play fundamental roles in development. They can be subdivided into several subfamilies, one of which is the LIM-homeobox subfamily. The primary structure of LIM-homeobox genes has been remarkably...
20.
Zhao Y, Guo Y, Tomac A, Taylor N, Grinberg A, Lee E, et al.
Proc Natl Acad Sci U S A
. 1999 Dec;
96(26):15002-6.
PMID: 10611327
Formation of the mammalian secondary palate is a highly regulated and complex process whose impairment often results in cleft palate, a common birth defect in both humans and animals. Loss-of-function...