H Ruskoaho
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Explore the profile of H Ruskoaho including associated specialties, affiliations and a list of published articles.
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164
Citations
1395
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Recent Articles
1.
Sakkinen H, Luosujarvi H, Karvonen T, Mustonen E, Moilanen A, Aro J, et al.
J Physiol Pharmacol
. 2024 Feb;
74(6).
PMID: 38345442
Dyxin is a LIM-domain containing transcriptional regulator protein shown to play a role in a hypertrophic response in the heart. Here, the effect of adenoviral dyxin overexpression was studied on...
2.
Fernandez C, Rysa J, Almgren P, Nilsson J, Engstrom G, Orho-Melander M, et al.
J Intern Med
. 2018 Jun;
284(4):377-387.
PMID: 29888466
Background: Diabetes mellitus is linked to premature mortality of virtually all causes. Furin is a proprotein convertase broadly involved in the maintenance of cellular homeostasis; however, little is known about...
3.
Kolto G, Vuolteenaho O, Szokodi I, Faludi R, Tornyos A, Ruskoaho H, et al.
Clin Exp Rheumatol
. 2014 Nov;
32(6 Suppl 86):S-75-81.
PMID: 25372791
Objectives: Cardiac involvement is an important determinant of prognosis in systemic sclerosis (SSc). The identification of patients with high risk is of great importance. Our aim was to investigate the...
4.
Rysa J, Buler M, Savolainen M, Ruskoaho H, Hakkola J, Hukkanen J
Clin Pharmacol Ther
. 2013 Apr;
93(6):556-63.
PMID: 23588309
We conducted a randomized, open, placebo-controlled crossover trial to investigate the effects of the pregnane X receptor (PXR) agonist rifampin on an oral glucose tolerance test (OGTT) in 12 healthy...
5.
Aro J, Tokola H, Ronkainen V, Koivisto E, Tenhunen O, Ilves M, et al.
Acta Physiol (Oxf)
. 2012 Dec;
207(3):470-84.
PMID: 23198998
Aim: Melusin is an integrin β1-interacting protein proposed to act as a biomechanical sensor in the heart. We characterized mechanisms and signalling pathways regulating cardiac melusin expression. Methods: Infusion of...
6.
Perjes A, Kubin A, Konyi A, Szabados S, Cziraki A, Skoumal R, et al.
Acta Physiol (Oxf)
. 2012 Apr;
205(1):26-40.
PMID: 22463609
Increased production of reactive oxygen species (ROS) has been linked to the pathogenesis of congestive heart failure. However, emerging evidence suggests the involvement of ROS in the regulation of various...
7.
Partanen N, Husso M, Vuolteenaho O, Sipola P, Ruskoaho H, Peuhkurinen K, et al.
J Hum Hypertens
. 2011 Jan;
25(12):746-51.
PMID: 21248782
Early detection of left ventricular hypertrophy (LVH) is beneficial, since treatment-induced regression of LVH has been unequivocally associated with a better prognosis. Our aim was to study the relation of...
8.
Mustonen E, Sakkinen H, Tokola H, Isopoussu E, Aro J, Leskinen H, et al.
Acta Physiol (Oxf)
. 2010 Jan;
199(1):11-22.
PMID: 20082609
Aim: Accumulating evidence supports the concept that proinflammatory cytokines play an essential role in the failing heart. We examined the concomitant tumour necrosis factor-like weak inducer of apoptosis (TWEAK)/Fn14 expression...
9.
Ola A, Kerkela R, Tokola H, Pikkarainen S, Skoumal R, Vuolteenaho O, et al.
Br J Pharmacol
. 2010 Jan;
159(3):717-25.
PMID: 20067472
Background And Purpose: The mixed-lineage kinases (MLKs) act upstream of mitogen-activated protein kinases, but their role in cardiac biology and pathology is largely unknown. Experimental Approach: We investigated the effect...
10.
Breuer T, Skoumal R, Horkay F, Merkely B, Ala-Kopsala M, Leppaluoto J, et al.
Acta Anaesthesiol Scand
. 2009 Nov;
54(4):502-9.
PMID: 19919584
Background: NT-proXNP, a new natriuretic peptide analyte, incorporates information about the concentrations of both N-terminal pro-atrial and pro-brain natriuretic peptides (NT-proANP, NT-proBNP). We aimed to investigate whether NT-proXNP is a...